Product Information
CIPROFLOXACIN HCL 500 MG TAB is a generic product labeled by Major Pharmaceuticals, priced at $0.1228 per EA under NDC 00904724395. Its NADAC has been published 167 times since Jul 26, 2023.
FDA first approved this application on Sep 10, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904724395
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CIPROFLOXACIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076639FDA Approved
9/10/2004
TE Code
AB
On Market Since
8/23/2022
Pharmacological Classes
Price Statistics
The NADAC for CIPROFLOXACIN HCL 500 MG TAB has been published 167 times since Jul 26, 2023, and over the history we have for it it has declined 16.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1228 per EA |
|---|---|
| All-time high | $0.1633 (Jan 10, 2024) |
| All-time low | $0.1084 (Nov 20, 2024) |
| 52-week high | $0.1387 |
| 52-week low | $0.1106 |
| Median price | $0.1387 |
| Average price | $0.1383 |
| Largest weekly change | -25.2% (Nov 20, 2024) |
| Weeks tracked | 167 |
| Tracking since | Jul 26, 2023 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Major Pharmaceuticals manufacturer profile
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Drug market
ciprofloxacin market comparison
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Therapeutic class
Fluoroquinolone Antibacterial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CIPROFLOXACIN HCL 500 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for CIPROFLOXACIN HCL 500 MG TAB, manufactured by Major Pharmaceuticals, is $0.1228 per EA (NDC 00904724395), effective Sep 30, 2026.
How has the price of CIPROFLOXACIN HCL 500 MG TAB changed over time?
Over the history we have for it, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has declined 16.8%. It has been tracked across 167 weekly CMS publications since Jul 26, 2023.
What are the highest and lowest recorded NADAC prices for CIPROFLOXACIN HCL 500 MG TAB?
Since Jul 26, 2023, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has ranged from a low of $0.1084 (Nov 20, 2024) to a high of $0.1633 (Jan 10, 2024), with a median of $0.1387 per EA.
Are there cheaper alternatives to CIPROFLOXACIN HCL 500 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CIPROFLOXACIN HCL 500 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures CIPROFLOXACIN HCL 500 MG TAB?
CIPROFLOXACIN HCL 500 MG TAB (NDC 00904724395) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.