Product Information
DIFLUNISAL 500 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $1.0427 per EA under NDC 14539067306. Its NADAC has been published 356 times since Sep 11, 2019.
FDA first approved this application on Mar 8, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Heritage Pharmaceuticals Inc.NDC
14539067306
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DIFLUNISALApproval Type
Generic (ANDA)
FDA Application
ANDA202845FDA Approved
3/8/2012
TE Code
AB
On Market Since
3/8/2012
Pharmacological Classes
Price Statistics
The NADAC for DIFLUNISAL 500 MG TABLET has been published 356 times since Sep 11, 2019, and over the history we have for it it has declined 15.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0427 per EA |
|---|---|
| All-time high | $1.4281 (Jun 10, 2020) |
| All-time low | $0.8327 (Dec 21, 2022) |
| 52-week high | $1.1995 |
| 52-week low | $1.0380 |
| Median price | $1.0961 |
| Average price | $1.1001 |
| Largest weekly change | -29.8% (Dec 21, 2022) |
| Weeks tracked | 356 |
| Tracking since | Sep 11, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIFLUNISAL 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for DIFLUNISAL 500 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $1.0427 per EA (NDC 14539067306), effective Aug 19, 2026.
How has the price of DIFLUNISAL 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for DIFLUNISAL 500 MG TABLET has declined 15.5%. It has been tracked across 356 weekly CMS publications since Sep 11, 2019.
What are the highest and lowest recorded NADAC prices for DIFLUNISAL 500 MG TABLET?
Since Sep 11, 2019, the NADAC for DIFLUNISAL 500 MG TABLET has ranged from a low of $0.8327 (Dec 21, 2022) to a high of $1.4281 (Jun 10, 2020), with a median of $1.0961 per EA.
Are there cheaper alternatives to DIFLUNISAL 500 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DIFLUNISAL 500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures DIFLUNISAL 500 MG TABLET?
DIFLUNISAL 500 MG TABLET (NDC 14539067306) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.