Diflunisal
7 NDCs across 4 manufacturers|6 Generic,1 Brand
Diflunisal is used to treat rheumatoid arthritis, osteoarthritis and pain, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Apr 19, 1982, and the first generic was approved Jul 31, 1992. FDA's Orange Book lists 3 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $1 million on Diflunisal across 9,373 claims for 3,361 beneficiaries.
Diflunisal is available as 7 NDCs from 4 manufacturers (6 generic, 1 brand), with NADAC prices from $1.04 to $22.87 per EA — the most expensive product costs about 22× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
7
6G / 1B
Manufacturers
4
competing in market
Price Spread
$1.04 – $22.87
per EA
7d Activity
avg +0.5% WoW · of 7 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
4 manufacturers producing DIFLUNISAL
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
DOLOBID 250 MG TABLET | $22.8653 per EA | — |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
DIFLUNISAL 500 MG TABLET | $1.0427 per EA | +0.45% |
Frequently Asked Questions
What is Diflunisal used to treat?
Diflunisal is used to treat rheumatoid arthritis, osteoarthritis and pain, per the National Library of Medicine's MED-RT classification.
When did Diflunisal become available as a generic?
FDA approved the first generic Diflunisal (ANDA) on Jul 31, 1992. The Orange Book currently lists 3 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Diflunisal?
In 2024, Medicare Part D spent $1 million on Diflunisal across 9,373 claims for 3,361 beneficiaries.
How many Diflunisal products are on the market?
The Diflunisal drug market contains 7 NDCs from 4 manufacturers — 6 generic and 1 brand product.
What is the price range for Diflunisal?
NADAC reference prices for Diflunisal range from $1.0427 to $22.8653 per EA — the most expensive product costs about 22× the cheapest.
Is generic Diflunisal cheaper than brand?
The average generic NADAC for Diflunisal is $1.0427 per EA, versus $22.8653 for brand-labeled products — brand versions average about 22× the generic price.
Which manufacturers make Diflunisal?
4 manufacturers list Diflunisal in NADAC. Ranked by number of NDCs, the largest are Teva Pharmaceuticals USA Inc. (3), Heritage Pharmaceuticals Inc. (2), INA Pharmaceutics Inc (1), Chartwell RX LLC (1).
How has the price of Diflunisal changed recently?
Over the past 7 days, 6 Diflunisal NDCs rose and 0 fell, with a market-wide average change of +0.5%.