Product Information
CIPROFLOXACIN HCL 500 MG TAB is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1228 per EA under NDC 16571041210. Its NADAC has been published 637 times since Nov 28, 2013.
FDA first approved this application on Sep 10, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
16571041210
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CIPROFLOXACIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076639FDA Approved
9/10/2004
TE Code
AB
On Market Since
9/10/2004
Pharmacological Classes
Price Statistics
The NADAC for CIPROFLOXACIN HCL 500 MG TAB has been published 637 times since Nov 28, 2013, and over the history we have for it it has declined 10.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1228 per EA |
|---|---|
| All-time high | $0.3128 (Aug 12, 2015) |
| All-time low | $0.1050 (Jul 22, 2020) |
| 52-week high | $0.1387 |
| 52-week low | $0.1106 |
| Median price | $0.1417 |
| Average price | $0.1441 |
| Largest weekly change | +68.2% (Jul 22, 2015) |
| Weeks tracked | 637 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
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Drug market
ciprofloxacin market comparison
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Therapeutic class
Fluoroquinolone Antibacterial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CIPROFLOXACIN HCL 500 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for CIPROFLOXACIN HCL 500 MG TAB, manufactured by Rising Pharma Holdings Inc., is $0.1228 per EA (NDC 16571041210), effective Sep 30, 2026.
How has the price of CIPROFLOXACIN HCL 500 MG TAB changed over time?
Over the history we have for it, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has declined 10.3%. It has been tracked across 637 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for CIPROFLOXACIN HCL 500 MG TAB?
Since Nov 28, 2013, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has ranged from a low of $0.1050 (Jul 22, 2020) to a high of $0.3128 (Aug 12, 2015), with a median of $0.1417 per EA.
Are there cheaper alternatives to CIPROFLOXACIN HCL 500 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CIPROFLOXACIN HCL 500 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures CIPROFLOXACIN HCL 500 MG TAB?
CIPROFLOXACIN HCL 500 MG TAB (NDC 16571041210) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.