Product Information

CIPROFLOXACIN HCL 500 MG TAB is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1244 per EA under NDC 16571041210. Its NADAC has been published 631 times since Nov 28, 2013.

FDA first approved this application on Sep 10, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CIPROFLOXACIN HCL 500 MG TAB

ciprofloxacin
$0.1244per EA

Strength

500 mg/1

NDC

16571041210

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CIPROFLOXACIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA076639

FDA Approved

9/10/2004

TE Code

AB

On Market Since

9/10/2004

Pharmacological Classes

Cytochrome P450 1A2 Inhibitors
Fluoroquinolone Antibacterial
Fluoroquinolones

Price Statistics

The NADAC for CIPROFLOXACIN HCL 500 MG TAB has been published 631 times since Nov 28, 2013, and over the history we have for it it has declined 9.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1244 per EA
All-time high$0.3128 (Aug 12, 2015)
All-time low$0.1050 (Jul 22, 2020)
52-week high$0.1397
52-week low$0.1106
Median price$0.1424
Average price$0.1442
Largest weekly change+68.2% (Jul 22, 2015)
Weeks tracked631
Tracking sinceNov 28, 2013

Price History

1W

-0.2%

1M

-0.2%

3M

+5.4%

6M

+0.5%

1Y

-11.0%

3Y

-15.8%

5Y

-17.3%

All

-9.1%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CIPROFLOXACIN HCL 500 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for CIPROFLOXACIN HCL 500 MG TAB, manufactured by Rising Pharma Holdings Inc., is $0.1244 per EA (NDC 16571041210), effective Aug 19, 2026.

How has the price of CIPROFLOXACIN HCL 500 MG TAB changed over time?

Over the history we have for it, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has declined 9.1%. It has been tracked across 631 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for CIPROFLOXACIN HCL 500 MG TAB?

Since Nov 28, 2013, the NADAC for CIPROFLOXACIN HCL 500 MG TAB has ranged from a low of $0.1050 (Jul 22, 2020) to a high of $0.3128 (Aug 12, 2015), with a median of $0.1424 per EA.

Are there cheaper alternatives to CIPROFLOXACIN HCL 500 MG TAB?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CIPROFLOXACIN HCL 500 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures CIPROFLOXACIN HCL 500 MG TAB?

CIPROFLOXACIN HCL 500 MG TAB (NDC 16571041210) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.