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Product Information

PROPAFENONE HCL ER 225 MG CAP is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.3557 per EA under NDC 16571073606. Its NADAC has been published 264 times since Aug 4, 2021.

FDA first approved this application on Jul 2, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL ER 225 MG CAP

PROPAFENONE HYDROCHLORIDE
$0.3557per EA

Strength

225 mg/1

NDC

16571073606

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205956

FDA Approved

7/2/2018

TE Code

AB

On Market Since

12/16/2020

Pharmacological Classes

Antiarrhythmic

Price Statistics

The NADAC for PROPAFENONE HCL ER 225 MG CAP has been published 264 times since Aug 4, 2021, and over the history we have for it it has declined 61.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3557 per EA
All-time high$1.6140 (Sep 15, 2021)
All-time low$0.3001 (May 20, 2026)
52-week high$0.4941
52-week low$0.3001
Median price$0.6972
Average price$0.7461
Largest weekly change+74.3% (Aug 18, 2021)
Weeks tracked264
Tracking sinceAug 4, 2021

Price History

1W

+2.6%

1M

+2.6%

3M

+18.5%

6M

+1.5%

1Y

-28.0%

3Y

-49.6%

5Y

-78.0%

All

-61.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the PROPAFENONE HYDROCHLORIDE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of PROPAFENONE HCL ER 225 MG CAP?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 225 MG CAP, manufactured by Rising Pharma Holdings Inc., is $0.3557 per EA (NDC 16571073606), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL ER 225 MG CAP changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL ER 225 MG CAP has declined 61.6%. It has been tracked across 264 weekly CMS publications since Aug 4, 2021.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 225 MG CAP?

Since Aug 4, 2021, the NADAC for PROPAFENONE HCL ER 225 MG CAP has ranged from a low of $0.3001 (May 20, 2026) to a high of $1.6140 (Sep 15, 2021), with a median of $0.6972 per EA.

Are there cheaper alternatives to PROPAFENONE HCL ER 225 MG CAP?

No other NADAC-published product currently shares the active ingredient and strength of PROPAFENONE HCL ER 225 MG CAP in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures PROPAFENONE HCL ER 225 MG CAP?

PROPAFENONE HCL ER 225 MG CAP (NDC 16571073606) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.