Product Information

PROPAFENONE HCL ER 425 MG CAP is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.5778 per EA under NDC 16571073806. Its NADAC has been published 129 times since Apr 17, 2024.

FDA first approved this application on Jul 2, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL ER 425 MG CAP

PROPAFENONE HYDROCHLORIDE
$0.5778per EA

Strength

425 mg/1

NDC

16571073806

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205956

FDA Approved

7/2/2018

TE Code

AB

On Market Since

12/16/2020

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL ER 425 MG CAP has been published 129 times since Apr 17, 2024, and over the history we have for it it has declined 58.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5778 per EA
All-time high$1.3963 (May 15, 2024)
All-time low$0.5637 (Jul 22, 2026)
52-week high$1.1142
52-week low$0.5637
Median price$0.9917
Average price$0.9527
Largest weekly change-26.2% (Jun 17, 2026)
Weeks tracked129
Tracking sinceApr 17, 2024

Price History

1W

0.0%

1M

+2.3%

3M

-14.7%

6M

-48.1%

1Y

-39.3%

3Y

N/A

5Y

N/A

All

-58.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the PROPAFENONE HYDROCHLORIDE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Continue researching this drug

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Frequently asked questions

What is the NADAC price of PROPAFENONE HCL ER 425 MG CAP?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 425 MG CAP, manufactured by Rising Pharma Holdings Inc., is $0.5778 per EA (NDC 16571073806), effective Sep 30, 2026.

How has the price of PROPAFENONE HCL ER 425 MG CAP changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL ER 425 MG CAP has declined 58.6%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 425 MG CAP?

Since Apr 17, 2024, the NADAC for PROPAFENONE HCL ER 425 MG CAP has ranged from a low of $0.5637 (Jul 22, 2026) to a high of $1.3963 (May 15, 2024), with a median of $0.9917 per EA.

Are there cheaper alternatives to PROPAFENONE HCL ER 425 MG CAP?

No other NADAC-published product currently shares the active ingredient and strength of PROPAFENONE HCL ER 425 MG CAP in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures PROPAFENONE HCL ER 425 MG CAP?

PROPAFENONE HCL ER 425 MG CAP (NDC 16571073806) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.