Product Information
PROBENECID 500 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.6361 per EA under NDC 16571083110. Its NADAC has been published 113 times since Aug 7, 2024.
FDA first approved this application on Nov 20, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
16571083110
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PROBENECIDApproval Type
Generic (ANDA)
FDA Application
ANDA217020FDA Approved
11/20/2023
TE Code
AB
On Market Since
11/20/2023
Price Statistics
The NADAC for PROBENECID 500 MG TABLET has been published 113 times since Aug 7, 2024, and over the history we have for it it has declined 12.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6361 per EA |
|---|---|
| All-time high | $1.0366 (Oct 16, 2024) |
| All-time low | $0.6339 (May 20, 2026) |
| 52-week high | $0.7708 |
| 52-week low | $0.6339 |
| Median price | $0.7708 |
| Average price | $0.7737 |
| Largest weekly change | +30.9% (Aug 21, 2024) |
| Weeks tracked | 113 |
| Tracking since | Aug 7, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
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Drug market
Probenecid market comparison
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of PROBENECID 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROBENECID 500 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.6361 per EA (NDC 16571083110), effective Sep 30, 2026.
How has the price of PROBENECID 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROBENECID 500 MG TABLET has declined 12.3%. It has been tracked across 113 weekly CMS publications since Aug 7, 2024.
What are the highest and lowest recorded NADAC prices for PROBENECID 500 MG TABLET?
Since Aug 7, 2024, the NADAC for PROBENECID 500 MG TABLET has ranged from a low of $0.6339 (May 20, 2026) to a high of $1.0366 (Oct 16, 2024), with a median of $0.7708 per EA.
Are there cheaper alternatives to PROBENECID 500 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROBENECID 500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROBENECID 500 MG TABLET?
PROBENECID 500 MG TABLET (NDC 16571083110) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.