Product Information
PENTOXIFYLLINE ER 400 MG TAB is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.2273 per EA under NDC 16571085650. Its NADAC has been published 96 times since Dec 4, 2024.
FDA first approved this application on Jul 8, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
16571085650
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PENTOXIFYLLINEApproval Type
Generic (ANDA)
FDA Application
ANDA074425FDA Approved
7/8/1997
TE Code
AB
On Market Since
6/11/2024
Pharmacological Classes
Price Statistics
The NADAC for PENTOXIFYLLINE ER 400 MG TAB has been published 96 times since Dec 4, 2024, and over the history we have for it it has declined 21.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2273 per EA |
|---|---|
| All-time high | $0.3087 (Jan 15, 2025) |
| All-time low | $0.2124 (Jul 23, 2025) |
| 52-week high | $0.2446 |
| 52-week low | $0.2180 |
| Median price | $0.2396 |
| Average price | $0.2472 |
| Largest weekly change | -8.8% (Jun 18, 2025) |
| Weeks tracked | 96 |
| Tracking since | Dec 4, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
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Drug market
Pentoxifylline market comparison
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Therapeutic class
Blood Viscosity Reducer class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PENTOXIFYLLINE ER 400 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for PENTOXIFYLLINE ER 400 MG TAB, manufactured by Rising Pharma Holdings Inc., is $0.2273 per EA (NDC 16571085650), effective Sep 30, 2026.
How has the price of PENTOXIFYLLINE ER 400 MG TAB changed over time?
Over the history we have for it, the NADAC for PENTOXIFYLLINE ER 400 MG TAB has declined 21.3%. It has been tracked across 96 weekly CMS publications since Dec 4, 2024.
What are the highest and lowest recorded NADAC prices for PENTOXIFYLLINE ER 400 MG TAB?
Since Dec 4, 2024, the NADAC for PENTOXIFYLLINE ER 400 MG TAB has ranged from a low of $0.2124 (Jul 23, 2025) to a high of $0.3087 (Jan 15, 2025), with a median of $0.2396 per EA.
Are there cheaper alternatives to PENTOXIFYLLINE ER 400 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PENTOXIFYLLINE ER 400 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures PENTOXIFYLLINE ER 400 MG TAB?
PENTOXIFYLLINE ER 400 MG TAB (NDC 16571085650) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.