Product Information
HYDROXYZINE HCL 25 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $0.0326 per EA under NDC 16714008211. Its NADAC has been published 660 times since Feb 12, 2014.
FDA first approved this application on Mar 31, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714008211
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROXYZINE DIHYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040840FDA Approved
3/31/2008
TE Code
AB
On Market Since
11/11/2009
Pharmacological Classes
Price Statistics
The NADAC for HYDROXYZINE HCL 25 MG TABLET has been published 660 times since Feb 12, 2014, and over the history we have for it it has declined 66.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0326 per EA |
|---|---|
| All-time high | $0.1062 (Apr 15, 2015) |
| All-time low | $0.0326 (Sep 23, 2026) |
| 52-week high | $0.0368 |
| 52-week low | $0.0326 |
| Median price | $0.0595 |
| Average price | $0.0631 |
| Largest weekly change | +60.2% (Jan 19, 2022) |
| Weeks tracked | 660 |
| Tracking since | Feb 12, 2014 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
NorthStar Rx LLC manufacturer profile
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Drug market
HydrOXYzine Hydrochloride market comparison
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Therapeutic class
Antihistamine class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROXYZINE HCL 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROXYZINE HCL 25 MG TABLET, manufactured by NorthStar Rx LLC, is $0.0326 per EA (NDC 16714008211), effective Sep 30, 2026.
How has the price of HYDROXYZINE HCL 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROXYZINE HCL 25 MG TABLET has declined 66.0%. It has been tracked across 660 weekly CMS publications since Feb 12, 2014.
What are the highest and lowest recorded NADAC prices for HYDROXYZINE HCL 25 MG TABLET?
Since Feb 12, 2014, the NADAC for HYDROXYZINE HCL 25 MG TABLET has ranged from a low of $0.0326 (Sep 23, 2026) to a high of $0.1062 (Apr 15, 2015), with a median of $0.0595 per EA.
Are there cheaper alternatives to HYDROXYZINE HCL 25 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROXYZINE HCL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROXYZINE HCL 25 MG TABLET?
HYDROXYZINE HCL 25 MG TABLET (NDC 16714008211) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.