Product Information
LIOTHYRONINE SOD 25 MCG TAB is a generic product labeled by NorthStar Rx LLC, priced at $0.2941 per EA under NDC 16714016701. Its NADAC has been published 262 times since Sep 29, 2021.
FDA first approved this application on Jan 22, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 ug/1
Manufacturer
NorthStar Rx LLCNDC
16714016701
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LIOTHYRONINE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA214803FDA Approved
1/22/2021
TE Code
AB
On Market Since
5/5/2021
Pharmacological Classes
Price Statistics
The NADAC for LIOTHYRONINE SOD 25 MCG TAB has been published 262 times since Sep 29, 2021, and over the history we have for it it has declined 36.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2941 per EA |
|---|---|
| All-time high | $0.5643 (Dec 15, 2021) |
| All-time low | $0.2458 (Nov 20, 2024) |
| 52-week high | $0.3431 |
| 52-week low | $0.2941 |
| Median price | $0.3856 |
| Average price | $0.3937 |
| Largest weekly change | +50.4% (Jun 19, 2024) |
| Weeks tracked | 262 |
| Tracking since | Sep 29, 2021 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
NorthStar Rx LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Liothyronine sodium market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
l-Triiodothyronine class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIOTHYRONINE SOD 25 MCG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LIOTHYRONINE SOD 25 MCG TAB, manufactured by NorthStar Rx LLC, is $0.2941 per EA (NDC 16714016701), effective Sep 30, 2026.
How has the price of LIOTHYRONINE SOD 25 MCG TAB changed over time?
Over the history we have for it, the NADAC for LIOTHYRONINE SOD 25 MCG TAB has declined 36.4%. It has been tracked across 262 weekly CMS publications since Sep 29, 2021.
What are the highest and lowest recorded NADAC prices for LIOTHYRONINE SOD 25 MCG TAB?
Since Sep 29, 2021, the NADAC for LIOTHYRONINE SOD 25 MCG TAB has ranged from a low of $0.2458 (Nov 20, 2024) to a high of $0.5643 (Dec 15, 2021), with a median of $0.3856 per EA.
Are there cheaper alternatives to LIOTHYRONINE SOD 25 MCG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIOTHYRONINE SOD 25 MCG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LIOTHYRONINE SOD 25 MCG TAB?
LIOTHYRONINE SOD 25 MCG TAB (NDC 16714016701) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.