Product Information
SIROLIMUS 2 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $2.5288 per EA under NDC 16714018901. Its NADAC has been published 155 times since Oct 18, 2023.
FDA first approved this application on Oct 16, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714018901
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
SIROLIMUSApproval Type
Generic (ANDA)
FDA Application
ANDA208691FDA Approved
10/16/2020
TE Code
AB
On Market Since
10/18/2021
Pharmacological Classes
Price Statistics
The NADAC for SIROLIMUS 2 MG TABLET has been published 155 times since Oct 18, 2023, and over the history we have for it it has declined 33.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5288 per EA |
|---|---|
| All-time high | $6.0804 (Aug 13, 2025) |
| All-time low | $2.5288 (Sep 23, 2026) |
| 52-week high | $5.3999 |
| 52-week low | $2.5288 |
| Median price | $4.4187 |
| Average price | $4.3829 |
| Largest weekly change | +29.7% (Dec 13, 2023) |
| Weeks tracked | 155 |
| Tracking since | Oct 18, 2023 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
NorthStar Rx LLC manufacturer profile
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Drug market
sirolimus market comparison
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Therapeutic class
Kinase Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SIROLIMUS 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SIROLIMUS 2 MG TABLET, manufactured by NorthStar Rx LLC, is $2.5288 per EA (NDC 16714018901), effective Sep 30, 2026.
How has the price of SIROLIMUS 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for SIROLIMUS 2 MG TABLET has declined 33.6%. It has been tracked across 155 weekly CMS publications since Oct 18, 2023.
What are the highest and lowest recorded NADAC prices for SIROLIMUS 2 MG TABLET?
Since Oct 18, 2023, the NADAC for SIROLIMUS 2 MG TABLET has ranged from a low of $2.5288 (Sep 23, 2026) to a high of $6.0804 (Aug 13, 2025), with a median of $4.4187 per EA.
Are there cheaper alternatives to SIROLIMUS 2 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SIROLIMUS 2 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SIROLIMUS 2 MG TABLET?
SIROLIMUS 2 MG TABLET (NDC 16714018901) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.