Product Information

SIROLIMUS 2 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $2.6413 per EA under NDC 68382035201. Its NADAC has been published 149 times since Oct 18, 2023.

FDA first approved this application on Jan 8, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SIROLIMUS 2 MG TABLET

sirolimus
$2.6413per EA

Strength

2 mg/1

NDC

68382035201

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SIROLIMUS

Approval Type

Generic (ANDA)

FDA Application

ANDA201676

FDA Approved

1/8/2014

TE Code

AB

On Market Since

2/16/2023

Pharmacological Classes

Decreased Immunologic Activity
Kinase Inhibitor
Protein Kinase Inhibitors
mTOR Inhibitor Immunosuppressant
mTOR Inhibitors

Price Statistics

The NADAC for SIROLIMUS 2 MG TABLET has been published 149 times since Oct 18, 2023, and over the history we have for it it has declined 30.6%. The table below summarizes its recorded NADAC range and movement.

Current price$2.6413 per EA
All-time high$6.0804 (Aug 13, 2025)
All-time low$2.6413 (Aug 19, 2026)
52-week high$5.8001
52-week low$2.6413
Median price$4.4680
Average price$4.4545
Largest weekly change+29.7% (Dec 13, 2023)
Weeks tracked149
Tracking sinceOct 18, 2023

Price History

1W

-5.9%

1M

-5.9%

3M

-13.1%

6M

-31.2%

1Y

-54.5%

3Y

N/A

5Y

N/A

All

-30.6%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SIROLIMUS 2 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SIROLIMUS 2 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $2.6413 per EA (NDC 68382035201), effective Aug 19, 2026.

How has the price of SIROLIMUS 2 MG TABLET changed over time?

Over the history we have for it, the NADAC for SIROLIMUS 2 MG TABLET has declined 30.6%. It has been tracked across 149 weekly CMS publications since Oct 18, 2023.

What are the highest and lowest recorded NADAC prices for SIROLIMUS 2 MG TABLET?

Since Oct 18, 2023, the NADAC for SIROLIMUS 2 MG TABLET has ranged from a low of $2.6413 (Aug 19, 2026) to a high of $6.0804 (Aug 13, 2025), with a median of $4.4680 per EA.

Are there cheaper alternatives to SIROLIMUS 2 MG TABLET?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SIROLIMUS 2 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SIROLIMUS 2 MG TABLET?

SIROLIMUS 2 MG TABLET (NDC 68382035201) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.