Product Information

PROPAFENONE HCL ER 325 MG CAP is a generic product labeled by NorthStar Rx LLC, priced at $0.5300 per EA under NDC 16714082601. Its NADAC has been published 354 times since Nov 13, 2019.

FDA first approved this application on Sep 8, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL ER 325 MG CAP

propafenone hydrochloride
$0.5300per EA

Strength

325 mg/1

Manufacturer

NorthStar Rx LLC

NDC

16714082601

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205268

FDA Approved

9/8/2017

TE Code

AB

On Market Since

3/31/2017

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL ER 325 MG CAP has been published 354 times since Nov 13, 2019, and over the history we have for it it has declined 86.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5300 per EA
All-time high$4.5892 (Apr 15, 2020)
All-time low$0.4264 (Feb 18, 2026)
52-week high$0.7614
52-week low$0.4264
Median price$1.1639
Average price$1.5222
Largest weekly change+97.6% (Oct 20, 2021)
Weeks tracked354
Tracking sinceNov 13, 2019

Price History

1W

+7.7%

1M

+7.7%

3M

+13.7%

6M

+24.3%

1Y

-30.4%

3Y

-54.6%

5Y

-76.2%

All

-86.0%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROPAFENONE HCL ER 325 MG CAP?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 325 MG CAP, manufactured by NorthStar Rx LLC, is $0.5300 per EA (NDC 16714082601), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL ER 325 MG CAP changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL ER 325 MG CAP has declined 86.0%. It has been tracked across 354 weekly CMS publications since Nov 13, 2019.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 325 MG CAP?

Since Nov 13, 2019, the NADAC for PROPAFENONE HCL ER 325 MG CAP has ranged from a low of $0.4264 (Feb 18, 2026) to a high of $4.5892 (Apr 15, 2020), with a median of $1.1639 per EA.

Are there cheaper alternatives to PROPAFENONE HCL ER 325 MG CAP?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 325 MG CAP in a comparable dosage form, but none are currently priced below it.

Who manufactures PROPAFENONE HCL ER 325 MG CAP?

PROPAFENONE HCL ER 325 MG CAP (NDC 16714082601) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.