Product Information
HYDROCHLOROTHIAZIDE 12.5 MG TB is a generic product labeled by Accord Healthcare Inc., priced at $0.0340 per EA under NDC 16729018217. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Sep 24, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729018217
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA202556FDA Approved
9/24/2012
TE Code
AB
On Market Since
4/18/2013
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 82.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0340 per EA |
|---|---|
| All-time high | $0.1912 (Dec 11, 2013) |
| All-time low | $0.0340 (Sep 23, 2026) |
| 52-week high | $0.0427 |
| 52-week low | $0.0340 |
| Median price | $0.0643 |
| Average price | $0.0760 |
| Largest weekly change | +51.5% (Jan 17, 2018) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Accord Healthcare Inc. manufacturer profile
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Drug market
Hydrochlorothiazide market comparison
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Therapeutic class
Thiazide Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 12.5 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 12.5 MG TB, manufactured by Accord Healthcare Inc., is $0.0340 per EA (NDC 16729018217), effective Sep 30, 2026.
How has the price of HYDROCHLOROTHIAZIDE 12.5 MG TB changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has declined 82.2%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 12.5 MG TB?
Since Nov 28, 2013, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG TB has ranged from a low of $0.0340 (Sep 23, 2026) to a high of $0.1912 (Dec 11, 2013), with a median of $0.0643 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 12.5 MG TB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 12.5 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCHLOROTHIAZIDE 12.5 MG TB?
HYDROCHLOROTHIAZIDE 12.5 MG TB (NDC 16729018217) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.