Product Information
HYDROCHLOROTHIAZIDE 50 MG TAB is a generic product labeled by Accord Healthcare Inc., priced at $0.0317 per EA under NDC 16729018417. Its NADAC has been published 572 times since Nov 28, 2013.
FDA first approved this application on Sep 24, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729018417
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
7/23/2025
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA202556FDA Approved
9/24/2012
TE Code
AB
On Market Since
4/10/2013
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 50 MG TAB has been published 572 times since Nov 28, 2013, and over the history we have for it it has declined 13.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0317 per EA |
|---|---|
| All-time high | $0.0394 (Jun 14, 2023) |
| All-time low | $0.0208 (Oct 17, 2018) |
| Median price | $0.0325 |
| Average price | $0.0320 |
| Largest weekly change | -20.8% (Aug 19, 2020) |
| Weeks tracked | 572 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-2.7%
5Y
+6.6%
All
-13.0%
Last surveyed Jul 30, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 50 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 50 MG TAB, manufactured by Accord Healthcare Inc., is $0.0317 per EA (NDC 16729018417), effective Jul 30, 2025.
How has the price of HYDROCHLOROTHIAZIDE 50 MG TAB changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 50 MG TAB has declined 13.0%. It has been tracked across 572 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 50 MG TAB?
Since Nov 28, 2013, the NADAC for HYDROCHLOROTHIAZIDE 50 MG TAB has ranged from a low of $0.0208 (Oct 17, 2018) to a high of $0.0394 (Jun 14, 2023), with a median of $0.0325 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 50 MG TAB?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCHLOROTHIAZIDE 50 MG TAB, is $0.0310 per EA — about 2% below HYDROCHLOROTHIAZIDE 50 MG TAB.
Who manufactures HYDROCHLOROTHIAZIDE 50 MG TAB?
HYDROCHLOROTHIAZIDE 50 MG TAB (NDC 16729018417) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.