Product Information
SERTRALINE HCL 25 MG TABLET is a generic product labeled by Accord Healthcare Inc., priced at $0.0298 per EA under NDC 16729021516. Its NADAC has been published 404 times since Aug 29, 2018.
FDA first approved this application on Nov 7, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729021516
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
5/20/2026
Active Ingredients
SERTRALINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA202825FDA Approved
11/7/2014
TE Code
AB
On Market Since
2/9/2017
Pharmacological Classes
Price Statistics
The NADAC for SERTRALINE HCL 25 MG TABLET has been published 404 times since Aug 29, 2018, and over the history we have for it it has declined 51.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0298 per EA |
|---|---|
| All-time high | $0.0786 (Sep 16, 2020) |
| All-time low | $0.0285 (Nov 20, 2024) |
| 52-week high | $0.0336 |
| 52-week low | $0.0298 |
| Median price | $0.0417 |
| Average price | $0.0489 |
| Largest weekly change | +31.1% (Jul 22, 2020) |
| Weeks tracked | 404 |
| Tracking since | Aug 29, 2018 |
1W
N/A
1M
N/A
3M
N/A
6M
-6.9%
1Y
-9.9%
3Y
-20.7%
5Y
-56.4%
All
-51.4%
Last surveyed May 20, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SERTRALINE HCL 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Accord Healthcare Inc., is $0.0298 per EA (NDC 16729021516), effective May 20, 2026.
How has the price of SERTRALINE HCL 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 51.4%. It has been tracked across 404 weekly CMS publications since Aug 29, 2018.
What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?
Since Aug 29, 2018, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0285 (Nov 20, 2024) to a high of $0.0786 (Sep 16, 2020), with a median of $0.0417 per EA.
Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SERTRALINE HCL 25 MG TABLET?
SERTRALINE HCL 25 MG TABLET (NDC 16729021516) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.