Product Information

SERTRALINE HCL 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0286 per EA under NDC 00904692461. Its NADAC has been published 284 times since Jan 20, 2021.

SERTRALINE HCL 25 MG TABLET

Sertraline Hydrochloride
$0.0286per EA

Strength

25 mg/1

NDC

00904692461

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077670

On Market Since

2/6/2007

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 25 MG TABLET has been published 284 times since Jan 20, 2021, and over the history we have for it it has declined 62.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0286 per EA
All-time high$0.0756 (Jul 14, 2021)
All-time low$0.0285 (Nov 20, 2024)
52-week high$0.0336
52-week low$0.0286
Median price$0.0379
Average price$0.0428
Largest weekly change-24.8% (Nov 20, 2024)
Weeks tracked284
Tracking sinceJan 20, 2021

Price History

1W

0.0%

1M

-3.8%

3M

-9.9%

6M

-13.0%

1Y

-11.3%

3Y

-31.4%

5Y

-62.1%

All

-62.1%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0286 per EA (NDC 00904692461), effective Jun 24, 2026.

How has the price of SERTRALINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 62.1%. It has been tracked across 284 weekly CMS publications since Jan 20, 2021.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?

Since Jan 20, 2021, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0285 (Nov 20, 2024) to a high of $0.0756 (Jul 14, 2021), with a median of $0.0379 per EA.

Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?

6 NADAC-published products share the same active ingredient, strength, and dosage form as SERTRALINE HCL 25 MG TABLET, but none are currently priced below it.

Who manufactures SERTRALINE HCL 25 MG TABLET?

SERTRALINE HCL 25 MG TABLET (NDC 00904692461) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.