Product Information
DESONIDE 0.05% OINTMENT is a generic product labeled by Encube Ethicals, Inc., priced at $0.4098 per GM under NDC 21922000404. Its NADAC has been published 355 times since Nov 6, 2019.
FDA first approved this application on Jan 30, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922000404
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210998FDA Approved
1/30/2019
TE Code
AB
On Market Since
3/20/2019
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% OINTMENT has been published 355 times since Nov 6, 2019, and over the history we have for it it has declined 71.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4098 per GM |
|---|---|
| All-time high | $2.1282 (Feb 10, 2021) |
| All-time low | $0.3624 (Nov 20, 2024) |
| 52-week high | $0.4692 |
| 52-week low | $0.3771 |
| Median price | $0.6996 |
| Average price | $0.8788 |
| Largest weekly change | +81.9% (Dec 23, 2020) |
| Weeks tracked | 355 |
| Tracking since | Nov 6, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 35% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% OINTMENT, manufactured by Encube Ethicals, Inc., is $0.4098 per GM (NDC 21922000404), effective Aug 19, 2026.
How has the price of DESONIDE 0.05% OINTMENT changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% OINTMENT has declined 71.3%. It has been tracked across 355 weekly CMS publications since Nov 6, 2019.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% OINTMENT?
Since Nov 6, 2019, the NADAC for DESONIDE 0.05% OINTMENT has ranged from a low of $0.3624 (Nov 20, 2024) to a high of $2.1282 (Feb 10, 2021), with a median of $0.6996 per GM.
Are there cheaper alternatives to DESONIDE 0.05% OINTMENT?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESONIDE 0.05% OINTMENT, is $0.2672 per GM — about 35% below DESONIDE 0.05% OINTMENT.
Who manufactures DESONIDE 0.05% OINTMENT?
DESONIDE 0.05% OINTMENT (NDC 21922000404) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.