Product Information

DESONIDE 0.05% OINTMENT is a generic product labeled by Encube Ethicals, Inc., priced at $0.3829 per GM under NDC 21922000404. Its NADAC has been published 347 times since Nov 6, 2019.

DESONIDE 0.05% OINTMENT

Desonide Ointment, 0.05%
$0.3829per GM

Strength

.5 mg/g

NDC

21922000404

Classification

Generic

Dosage Form

OINTMENT

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

DESONIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA210998

On Market Since

3/20/2019

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for DESONIDE 0.05% OINTMENT has been published 347 times since Nov 6, 2019, and over the history we have for it it has declined 73.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3829 per GM
All-time high$2.1282 (Feb 10, 2021)
All-time low$0.3624 (Nov 20, 2024)
52-week high$0.4692
52-week low$0.3771
Median price$0.7087
Average price$0.8901
Largest weekly change+81.9% (Dec 23, 2020)
Weeks tracked347
Tracking sinceNov 6, 2019

Price History

1W

0.0%

1M

-1.7%

3M

-4.3%

6M

-13.4%

1Y

-17.8%

3Y

-42.5%

5Y

-72.2%

All

-73.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 31% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 31%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of DESONIDE 0.05% OINTMENT?

The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% OINTMENT, manufactured by Encube Ethicals, Inc., is $0.3829 per GM (NDC 21922000404), effective Jun 24, 2026.

How has the price of DESONIDE 0.05% OINTMENT changed over time?

Over the history we have for it, the NADAC for DESONIDE 0.05% OINTMENT has declined 73.1%. It has been tracked across 347 weekly CMS publications since Nov 6, 2019.

What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% OINTMENT?

Since Nov 6, 2019, the NADAC for DESONIDE 0.05% OINTMENT has ranged from a low of $0.3624 (Nov 20, 2024) to a high of $2.1282 (Feb 10, 2021), with a median of $0.7087 per GM.

Are there cheaper alternatives to DESONIDE 0.05% OINTMENT?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, DESONIDE 0.05% OINTMENT, is $0.2630 per GM — about 31% below DESONIDE 0.05% OINTMENT.

Who manufactures DESONIDE 0.05% OINTMENT?

DESONIDE 0.05% OINTMENT (NDC 21922000404) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.