Product Information
DESONIDE 0.05% OINTMENT is a generic product labeled by Encube Ethicals, Inc., priced at $0.2672 per GM under NDC 21922000407. Its NADAC has been published 355 times since Nov 6, 2019.
FDA first approved this application on Jan 30, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922000407
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210998FDA Approved
1/30/2019
TE Code
AB
On Market Since
3/20/2019
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% OINTMENT has been published 355 times since Nov 6, 2019, and over the history we have for it it has declined 75.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2672 per GM |
|---|---|
| All-time high | $1.6276 (Dec 11, 2019) |
| All-time low | $0.2349 (Mar 18, 2026) |
| 52-week high | $0.3605 |
| 52-week low | $0.2349 |
| Median price | $0.5401 |
| Average price | $0.6668 |
| Largest weekly change | +71.8% (Nov 22, 2023) |
| Weeks tracked | 355 |
| Tracking since | Nov 6, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% OINTMENT, manufactured by Encube Ethicals, Inc., is $0.2672 per GM (NDC 21922000407), effective Aug 19, 2026.
How has the price of DESONIDE 0.05% OINTMENT changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% OINTMENT has declined 75.4%. It has been tracked across 355 weekly CMS publications since Nov 6, 2019.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% OINTMENT?
Since Nov 6, 2019, the NADAC for DESONIDE 0.05% OINTMENT has ranged from a low of $0.2349 (Mar 18, 2026) to a high of $1.6276 (Dec 11, 2019), with a median of $0.5401 per GM.
Are there cheaper alternatives to DESONIDE 0.05% OINTMENT?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures DESONIDE 0.05% OINTMENT?
DESONIDE 0.05% OINTMENT (NDC 21922000407) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.