Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.1211 per GM under NDC 21922001606. Its NADAC has been published 296 times since Oct 28, 2020.
Strength
.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922001606
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA212982On Market Since
10/1/2020
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 296 times since Oct 28, 2020, and over the history we have for it it has declined 86.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1211 per GM |
|---|---|
| All-time high | $0.8927 (Mar 10, 2021) |
| All-time low | $0.0808 (Nov 20, 2024) |
| 52-week high | $0.1526 |
| 52-week low | $0.1211 |
| Median price | $0.1772 |
| Average price | $0.2790 |
| Largest weekly change | +45.4% (Aug 21, 2024) |
| Weeks tracked | 296 |
| Tracking since | Oct 28, 2020 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Encube Ethicals, Inc., is $0.1211 per GM (NDC 21922001606), effective Jun 24, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 86.0%. It has been tracked across 296 weekly CMS publications since Oct 28, 2020.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Oct 28, 2020, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.0808 (Nov 20, 2024) to a high of $0.8927 (Mar 10, 2021), with a median of $0.1772 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
2 NADAC-published products share the same active ingredient, strength, and dosage form as CLOBETASOL 0.05% CREAM, but none are currently priced below it.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 21922001606) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.
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Same classification