Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.1158 per GM under NDC 72603032303. Its NADAC has been published 77 times since Mar 5, 2025.
FDA first approved this application on Aug 28, 2020. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
NorthStar Rx LLCNDC
72603032303
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA212982FDA Approved
8/28/2020
TE Code
AB1
On Market Since
11/1/2024
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 77 times since Mar 5, 2025, and over the history we have for it it has declined 2.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1158 per GM |
|---|---|
| All-time high | $0.1526 (Sep 10, 2025) |
| All-time low | $0.1096 (Jul 22, 2026) |
| 52-week high | $0.1526 |
| 52-week low | $0.1096 |
| Median price | $0.1362 |
| Average price | $0.1347 |
| Largest weekly change | +10.3% (Mar 19, 2025) |
| Weeks tracked | 77 |
| Tracking since | Mar 5, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by NorthStar Rx LLC, is $0.1158 per GM (NDC 72603032303), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 2.2%. It has been tracked across 77 weekly CMS publications since Mar 5, 2025.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Mar 5, 2025, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1096 (Jul 22, 2026) to a high of $0.1526 (Sep 10, 2025), with a median of $0.1362 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CLOBETASOL 0.05% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 72603032303) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.