Product Information
KETOCONAZOLE 2% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.3029 per GM under NDC 21922002504. Its NADAC has been published 270 times since Jun 23, 2021.
FDA first approved this application on May 20, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
20 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922002504
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
KETOCONAZOLEApproval Type
Generic (ANDA)
FDA Application
ANDA212443FDA Approved
5/20/2021
TE Code
AB
On Market Since
5/27/2021
Pharmacological Classes
Price Statistics
The NADAC for KETOCONAZOLE 2% CREAM has been published 270 times since Jun 23, 2021, and over the history we have for it it has declined 46.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3029 per GM |
|---|---|
| All-time high | $0.6028 (Sep 15, 2021) |
| All-time low | $0.2119 (Jul 17, 2024) |
| 52-week high | $0.3514 |
| 52-week low | $0.3029 |
| Median price | $0.3121 |
| Average price | $0.3435 |
| Largest weekly change | +28.7% (Aug 21, 2024) |
| Weeks tracked | 270 |
| Tracking since | Jun 23, 2021 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 46% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of KETOCONAZOLE 2% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for KETOCONAZOLE 2% CREAM, manufactured by Encube Ethicals, Inc., is $0.3029 per GM (NDC 21922002504), effective Aug 19, 2026.
How has the price of KETOCONAZOLE 2% CREAM changed over time?
Over the history we have for it, the NADAC for KETOCONAZOLE 2% CREAM has declined 46.8%. It has been tracked across 270 weekly CMS publications since Jun 23, 2021.
What are the highest and lowest recorded NADAC prices for KETOCONAZOLE 2% CREAM?
Since Jun 23, 2021, the NADAC for KETOCONAZOLE 2% CREAM has ranged from a low of $0.2119 (Jul 17, 2024) to a high of $0.6028 (Sep 15, 2021), with a median of $0.3121 per GM.
Are there cheaper alternatives to KETOCONAZOLE 2% CREAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, KETOCONAZOLE 2% CREAM, is $0.1628 per GM — about 46% below KETOCONAZOLE 2% CREAM.
Who manufactures KETOCONAZOLE 2% CREAM?
KETOCONAZOLE 2% CREAM (NDC 21922002504) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.