Product Information

KETOCONAZOLE 2% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.3107 per GM under NDC 21922002504. Its NADAC has been published 263 times since Jun 23, 2021.

KETOCONAZOLE 2% CREAM

Ketoconazole Cream, 2%
$0.3107per GM

Strength

20 mg/g

NDC

21922002504

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

KETOCONAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA212443

On Market Since

5/27/2021

Pharmacological Classes

Azole Antifungal
Azoles
Cytochrome P450 3A4 Inhibitors
Cytochrome P450 3A5 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for KETOCONAZOLE 2% CREAM has been published 263 times since Jun 23, 2021, and over the history we have for it it has declined 45.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3107 per GM
All-time high$0.6028 (Sep 15, 2021)
All-time low$0.2119 (Jul 17, 2024)
52-week high$0.3514
52-week low$0.2997
Median price$0.3136
Average price$0.3444
Largest weekly change+28.7% (Aug 21, 2024)
Weeks tracked263
Tracking sinceJun 23, 2021

Price History

1W

0.0%

1M

+2.1%

3M

-0.9%

6M

-9.8%

1Y

+3.6%

3Y

+15.5%

5Y

-45.5%

All

-45.5%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 47% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 47%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of KETOCONAZOLE 2% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for KETOCONAZOLE 2% CREAM, manufactured by Encube Ethicals, Inc., is $0.3107 per GM (NDC 21922002504), effective Jul 1, 2026.

How has the price of KETOCONAZOLE 2% CREAM changed over time?

Over the history we have for it, the NADAC for KETOCONAZOLE 2% CREAM has declined 45.5%. It has been tracked across 263 weekly CMS publications since Jun 23, 2021.

What are the highest and lowest recorded NADAC prices for KETOCONAZOLE 2% CREAM?

Since Jun 23, 2021, the NADAC for KETOCONAZOLE 2% CREAM has ranged from a low of $0.2119 (Jul 17, 2024) to a high of $0.6028 (Sep 15, 2021), with a median of $0.3136 per GM.

Are there cheaper alternatives to KETOCONAZOLE 2% CREAM?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, KETOCONAZOLE 2% CREAM, is $0.1633 per GM — about 47% below KETOCONAZOLE 2% CREAM.

Who manufactures KETOCONAZOLE 2% CREAM?

KETOCONAZOLE 2% CREAM (NDC 21922002504) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.