Product Information

KETOCONAZOLE 2% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.1628 per GM under NDC 21922002507. Its NADAC has been published 270 times since Jun 23, 2021.

FDA first approved this application on May 20, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

KETOCONAZOLE 2% CREAM

Ketoconazole Cream, 2%
$0.1628per GM

Strength

20 mg/g

NDC

21922002507

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

KETOCONAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA212443

FDA Approved

5/20/2021

TE Code

AB

On Market Since

5/27/2021

Pharmacological Classes

Azole Antifungal
Azoles
Cytochrome P450 3A4 Inhibitors
Cytochrome P450 3A5 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for KETOCONAZOLE 2% CREAM has been published 270 times since Jun 23, 2021, and over the history we have for it it has declined 51.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1628 per GM
All-time high$0.4231 (Aug 11, 2021)
All-time low$0.1385 (Nov 20, 2024)
52-week high$0.1881
52-week low$0.1628
Median price$0.2028
Average price$0.2280
Largest weekly change+25.7% (Jul 21, 2021)
Weeks tracked270
Tracking sinceJun 23, 2021

Price History

1W

-0.2%

1M

-0.2%

3M

-4.5%

6M

-12.1%

1Y

-11.3%

3Y

-26.3%

5Y

-58.6%

All

-51.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of KETOCONAZOLE 2% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for KETOCONAZOLE 2% CREAM, manufactured by Encube Ethicals, Inc., is $0.1628 per GM (NDC 21922002507), effective Aug 19, 2026.

How has the price of KETOCONAZOLE 2% CREAM changed over time?

Over the history we have for it, the NADAC for KETOCONAZOLE 2% CREAM has declined 51.6%. It has been tracked across 270 weekly CMS publications since Jun 23, 2021.

What are the highest and lowest recorded NADAC prices for KETOCONAZOLE 2% CREAM?

Since Jun 23, 2021, the NADAC for KETOCONAZOLE 2% CREAM has ranged from a low of $0.1385 (Nov 20, 2024) to a high of $0.4231 (Aug 11, 2021), with a median of $0.2028 per GM.

Are there cheaper alternatives to KETOCONAZOLE 2% CREAM?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as KETOCONAZOLE 2% CREAM in a comparable dosage form, but none are currently priced below it.

Who manufactures KETOCONAZOLE 2% CREAM?

KETOCONAZOLE 2% CREAM (NDC 21922002507) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.