Product Information

KETOCONAZOLE 2% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.2562 per GM under NDC 21922002505. Its NADAC has been published 263 times since Jun 23, 2021.

KETOCONAZOLE 2% CREAM

Ketoconazole Cream, 2%
$0.2562per GM

Strength

20 mg/g

NDC

21922002505

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

KETOCONAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA212443

On Market Since

5/27/2021

Pharmacological Classes

Azole Antifungal
Azoles
Cytochrome P450 3A4 Inhibitors
Cytochrome P450 3A5 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for KETOCONAZOLE 2% CREAM has been published 263 times since Jun 23, 2021, and over the history we have for it it has declined 52.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2562 per GM
All-time high$0.5722 (Aug 11, 2021)
All-time low$0.1948 (Nov 20, 2024)
52-week high$0.2833
52-week low$0.2486
Median price$0.2719
Average price$0.3071
Largest weekly change-25.1% (Nov 20, 2024)
Weeks tracked263
Tracking sinceJun 23, 2021

Price History

1W

0.0%

1M

+2.1%

3M

+3.0%

6M

-6.0%

1Y

-3.4%

3Y

+2.7%

5Y

-52.7%

All

-52.7%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 36% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 36%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of KETOCONAZOLE 2% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for KETOCONAZOLE 2% CREAM, manufactured by Encube Ethicals, Inc., is $0.2562 per GM (NDC 21922002505), effective Jul 1, 2026.

How has the price of KETOCONAZOLE 2% CREAM changed over time?

Over the history we have for it, the NADAC for KETOCONAZOLE 2% CREAM has declined 52.7%. It has been tracked across 263 weekly CMS publications since Jun 23, 2021.

What are the highest and lowest recorded NADAC prices for KETOCONAZOLE 2% CREAM?

Since Jun 23, 2021, the NADAC for KETOCONAZOLE 2% CREAM has ranged from a low of $0.1948 (Nov 20, 2024) to a high of $0.5722 (Aug 11, 2021), with a median of $0.2719 per GM.

Are there cheaper alternatives to KETOCONAZOLE 2% CREAM?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, KETOCONAZOLE 2% CREAM, is $0.1633 per GM — about 36% below KETOCONAZOLE 2% CREAM.

Who manufactures KETOCONAZOLE 2% CREAM?

KETOCONAZOLE 2% CREAM (NDC 21922002505) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.