Product Information
CLINDA-TRETINOIN 1.2%-0.025% is a generic product labeled by Encube Ethicals, Inc., priced at $4.3282 per GM under NDC 21922005005. Its NADAC has been published 124 times since Apr 10, 2024.
FDA first approved this application on Sep 1, 2023. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10; .25 mg/g; mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922005005
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLINDAMYCIN PHOSPHATE; TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA216943FDA Approved
9/1/2023
TE Code
AB2
On Market Since
9/4/2023
Pharmacological Classes
Price Statistics
The NADAC for CLINDA-TRETINOIN 1.2%-0.025% has been published 124 times since Apr 10, 2024, and over the history we have for it it has declined 33.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.3282 per GM |
|---|---|
| All-time high | $6.5446 (Apr 10, 2024) |
| All-time low | $4.3282 (Aug 19, 2026) |
| 52-week high | $4.9717 |
| 52-week low | $4.3282 |
| Median price | $4.9448 |
| Average price | $5.0669 |
| Largest weekly change | -25.0% (Apr 17, 2024) |
| Weeks tracked | 124 |
| Tracking since | Apr 10, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLINDA-TRETINOIN 1.2%-0.025%?
The current National Average Drug Acquisition Cost (NADAC) for CLINDA-TRETINOIN 1.2%-0.025%, manufactured by Encube Ethicals, Inc., is $4.3282 per GM (NDC 21922005005), effective Aug 19, 2026.
How has the price of CLINDA-TRETINOIN 1.2%-0.025% changed over time?
Over the history we have for it, the NADAC for CLINDA-TRETINOIN 1.2%-0.025% has declined 33.9%. It has been tracked across 124 weekly CMS publications since Apr 10, 2024.
What are the highest and lowest recorded NADAC prices for CLINDA-TRETINOIN 1.2%-0.025%?
Since Apr 10, 2024, the NADAC for CLINDA-TRETINOIN 1.2%-0.025% has ranged from a low of $4.3282 (Aug 19, 2026) to a high of $6.5446 (Apr 10, 2024), with a median of $4.9448 per GM.
Are there cheaper alternatives to CLINDA-TRETINOIN 1.2%-0.025%?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLINDA-TRETINOIN 1.2%-0.025%, is $3.3975 per GM — about 22% below CLINDA-TRETINOIN 1.2%-0.025%.
Who manufactures CLINDA-TRETINOIN 1.2%-0.025%?
CLINDA-TRETINOIN 1.2%-0.025% (NDC 21922005005) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.