Product Information
CLINDA-TRETINOIN 1.2%-0.025% is a generic product labeled by Encube Ethicals, Inc., priced at $3.3975 per GM under NDC 21922005007. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Sep 1, 2023. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10; .25 mg/g; mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922005007
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLINDAMYCIN PHOSPHATE; TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA216943FDA Approved
9/1/2023
TE Code
AB2
On Market Since
9/4/2023
Pharmacological Classes
Price Statistics
The NADAC for CLINDA-TRETINOIN 1.2%-0.025% has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 36.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.3975 per GM |
|---|---|
| All-time high | $6.9072 (Aug 13, 2025) |
| All-time low | $3.3975 (Aug 19, 2026) |
| 52-week high | $6.5652 |
| 52-week low | $3.3975 |
| Median price | $5.0953 |
| Average price | $5.1392 |
| Largest weekly change | -19.3% (Mar 18, 2026) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLINDA-TRETINOIN 1.2%-0.025%?
The current National Average Drug Acquisition Cost (NADAC) for CLINDA-TRETINOIN 1.2%-0.025%, manufactured by Encube Ethicals, Inc., is $3.3975 per GM (NDC 21922005007), effective Aug 19, 2026.
How has the price of CLINDA-TRETINOIN 1.2%-0.025% changed over time?
Over the history we have for it, the NADAC for CLINDA-TRETINOIN 1.2%-0.025% has declined 36.3%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for CLINDA-TRETINOIN 1.2%-0.025%?
Since Apr 17, 2024, the NADAC for CLINDA-TRETINOIN 1.2%-0.025% has ranged from a low of $3.3975 (Aug 19, 2026) to a high of $6.9072 (Aug 13, 2025), with a median of $5.0953 per GM.
Are there cheaper alternatives to CLINDA-TRETINOIN 1.2%-0.025%?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as CLINDA-TRETINOIN 1.2%-0.025% in a comparable dosage form, but none are currently priced below it.
Who manufactures CLINDA-TRETINOIN 1.2%-0.025%?
CLINDA-TRETINOIN 1.2%-0.025% (NDC 21922005007) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.