Product Information
LEFLUNOMIDE 20 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.2944 per EA under NDC 23155004403. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Sep 13, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
20 mg/1
Manufacturer
Heritage Pharmaceuticals Inc.NDC
23155004403
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LEFLUNOMIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077086FDA Approved
9/13/2005
TE Code
AB
On Market Since
10/29/2009
Pharmacological Classes
Price Statistics
The NADAC for LEFLUNOMIDE 20 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 30.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2944 per EA |
|---|---|
| All-time high | $5.0165 (Jan 13, 2016) |
| All-time low | $0.2856 (Nov 20, 2024) |
| 52-week high | $0.3252 |
| 52-week low | $0.2884 |
| Median price | $0.6893 |
| Average price | $1.3840 |
| Largest weekly change | +193.5% (Jul 22, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Heritage Pharmaceuticals Inc. manufacturer profile
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Drug market
leflunomide market comparison
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Therapeutic class
Antirheumatic Agent class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LEFLUNOMIDE 20 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LEFLUNOMIDE 20 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $0.2944 per EA (NDC 23155004403), effective Sep 30, 2026.
How has the price of LEFLUNOMIDE 20 MG TABLET changed over time?
Over the history we have for it, the NADAC for LEFLUNOMIDE 20 MG TABLET has declined 30.1%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LEFLUNOMIDE 20 MG TABLET?
Since Nov 28, 2013, the NADAC for LEFLUNOMIDE 20 MG TABLET has ranged from a low of $0.2856 (Nov 20, 2024) to a high of $5.0165 (Jan 13, 2016), with a median of $0.6893 per EA.
Are there cheaper alternatives to LEFLUNOMIDE 20 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LEFLUNOMIDE 20 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LEFLUNOMIDE 20 MG TABLET?
LEFLUNOMIDE 20 MG TABLET (NDC 23155004403) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.