Product Information
GLYBURIDE-METFORMIN 2.5-500 MG is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.1824 per EA under NDC 23155023401. Its NADAC has been published 311 times since Nov 28, 2013.
FDA first approved this application on Jun 3, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5; 500 mg/1; mg/1
Manufacturer
Heritage Pharmaceuticals Inc.NDC
23155023401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
GLYBURIDE; METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA079009FDA Approved
6/3/2009
TE Code
AB
On Market Since
5/1/2024
Pharmacological Classes
Price Statistics
The NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has been published 311 times since Nov 28, 2013, and over the history we have for it it has risen 125.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1824 per EA |
|---|---|
| All-time high | $0.2036 (Mar 11, 2026) |
| All-time low | $0.0496 (Apr 18, 2018) |
| 52-week high | $0.2036 |
| 52-week low | $0.1663 |
| Median price | $0.0776 |
| Average price | $0.0933 |
| Largest weekly change | +41.1% (Apr 23, 2025) |
| Weeks tracked | 311 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 66% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GLYBURIDE-METFORMIN 2.5-500 MG?
The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 2.5-500 MG, manufactured by Heritage Pharmaceuticals Inc., is $0.1824 per EA (NDC 23155023401), effective Aug 19, 2026.
How has the price of GLYBURIDE-METFORMIN 2.5-500 MG changed over time?
Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has risen 125.0%. It has been tracked across 311 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 2.5-500 MG?
Since Nov 28, 2013, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has ranged from a low of $0.0496 (Apr 18, 2018) to a high of $0.2036 (Mar 11, 2026), with a median of $0.0776 per EA.
Are there cheaper alternatives to GLYBURIDE-METFORMIN 2.5-500 MG?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GLYBURIDE-METFORMIN 2.5-500 MG, is $0.0629 per EA — about 66% below GLYBURIDE-METFORMIN 2.5-500 MG.
Who manufactures GLYBURIDE-METFORMIN 2.5-500 MG?
GLYBURIDE-METFORMIN 2.5-500 MG (NDC 23155023401) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.