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Product Information

GLYBURIDE-METFORMIN 5-500 MG is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.1882 per EA under NDC 23155023501. Its NADAC has been published 327 times since Nov 28, 2013.

FDA first approved this application on Jun 3, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

GLYBURIDE-METFORMIN 5-500 MG

glyburide-metformin hydrochloride
$0.1882per EA

Strength

5; 500 mg/1; mg/1

NDC

23155023501

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA079009

FDA Approved

6/3/2009

TE Code

AB

On Market Since

5/1/2024

Pharmacological Classes

Biguanide
Biguanides
Sulfonylurea Compounds
Sulfonylurea

Price Statistics

The NADAC for GLYBURIDE-METFORMIN 5-500 MG has been published 327 times since Nov 28, 2013, and over the history we have for it it has risen 143.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1882 per EA
All-time high$0.2013 (Jan 14, 2026)
All-time low$0.0474 (Nov 20, 2024)
52-week high$0.2013
52-week low$0.1804
Median price$0.0767
Average price$0.0996
Largest weekly change+83.1% (Dec 18, 2024)
Weeks tracked327
Tracking sinceNov 28, 2013

Price History

1W

+2.3%

1M

+2.3%

3M

+4.3%

6M

-3.7%

1Y

+1.1%

3Y

+201.3%

5Y

+201.3%

All

+143.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 67% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 67%

1 alternative • Same active ingredient

GLYBURIDE-METFORMIN 5-500 MG
Generic
23155023505•Heritage Pharmaceuticals Inc.
$0.0624
Save 67%

Related Drugs

Same classification

METFORMIN HCL 500 MG TABLET
Generic
71093013204•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
71093013205•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
71093013206•ACI Healthcare USA, Inc.
$0.0140
per EA
METFORMIN HCL 500 MG TABLET
Generic
00378718505•Mylan Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
00904716261•Major Pharmaceuticals
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084101•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084105•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
23155084110•Heritage Pharmaceuticals Inc.
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094701•Laurus Labs Limited
$0.0142
per EA
METFORMIN HCL 500 MG TABLET
Generic
42385094705•Laurus Labs Limited
$0.0142
per EA

Frequently asked questions

What is the NADAC price of GLYBURIDE-METFORMIN 5-500 MG?

The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 5-500 MG, manufactured by Heritage Pharmaceuticals Inc., is $0.1882 per EA (NDC 23155023501), effective Aug 19, 2026.

How has the price of GLYBURIDE-METFORMIN 5-500 MG changed over time?

Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 5-500 MG has risen 143.9%. It has been tracked across 327 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 5-500 MG?

Since Nov 28, 2013, the NADAC for GLYBURIDE-METFORMIN 5-500 MG has ranged from a low of $0.0474 (Nov 20, 2024) to a high of $0.2013 (Jan 14, 2026), with a median of $0.0767 per EA.

Are there cheaper alternatives to GLYBURIDE-METFORMIN 5-500 MG?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GLYBURIDE-METFORMIN 5-500 MG, is $0.0624 per EA — about 67% below GLYBURIDE-METFORMIN 5-500 MG.

Who manufactures GLYBURIDE-METFORMIN 5-500 MG?

GLYBURIDE-METFORMIN 5-500 MG (NDC 23155023501) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.