Product Information
CYANOCOBALAMIN 1,000 MCG/ML VL is a generic product labeled by Sagent Pharmaceuticals, priced at $1.4739 per ML under NDC 25021050201. Its NADAC has been published 173 times since Jun 14, 2023.
FDA first approved this application on Nov 15, 2022. Its Orange Book therapeutic-equivalence code is AP.
Strength
1000 ug/mL
Manufacturer
Sagent PharmaceuticalsNDC
25021050201
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
CYANOCOBALAMINApproval Type
Generic (ANDA)
FDA Application
ANDA215107FDA Approved
11/15/2022
TE Code
AP
On Market Since
3/15/2023
Pharmacological Classes
Price Statistics
The NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has been published 173 times since Jun 14, 2023, and over the history we have for it it has declined 44.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4739 per ML |
|---|---|
| All-time high | $2.7100 (Oct 11, 2023) |
| All-time low | $1.4739 (Sep 23, 2026) |
| 52-week high | $1.6529 |
| 52-week low | $1.4739 |
| Median price | $1.7618 |
| Average price | $1.9032 |
| Largest weekly change | +39.2% (Aug 21, 2024) |
| Weeks tracked | 173 |
| Tracking since | Jun 14, 2023 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 78% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Sagent Pharmaceuticals manufacturer profile
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Drug market
Cyanocobalamin market comparison
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Therapeutic class
Vitamin B12 class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CYANOCOBALAMIN 1,000 MCG/ML VL?
The current National Average Drug Acquisition Cost (NADAC) for CYANOCOBALAMIN 1,000 MCG/ML VL, manufactured by Sagent Pharmaceuticals, is $1.4739 per ML (NDC 25021050201), effective Sep 30, 2026.
How has the price of CYANOCOBALAMIN 1,000 MCG/ML VL changed over time?
Over the history we have for it, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has declined 44.1%. It has been tracked across 173 weekly CMS publications since Jun 14, 2023.
What are the highest and lowest recorded NADAC prices for CYANOCOBALAMIN 1,000 MCG/ML VL?
Since Jun 14, 2023, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has ranged from a low of $1.4739 (Sep 23, 2026) to a high of $2.7100 (Oct 11, 2023), with a median of $1.7618 per ML.
Are there cheaper alternatives to CYANOCOBALAMIN 1,000 MCG/ML VL?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYANOCOBALAMIN 30,000 MCG/30 ML, is $0.3281 per ML — about 78% below CYANOCOBALAMIN 1,000 MCG/ML VL.
Who manufactures CYANOCOBALAMIN 1,000 MCG/ML VL?
CYANOCOBALAMIN 1,000 MCG/ML VL (NDC 25021050201) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.