Product Information

RANOLAZINE ER 500 MG TABLET is a generic product labeled by Ajanta Pharma USA Inc., priced at $0.1649 per EA under NDC 27241012502. Its NADAC has been published 372 times since Aug 21, 2019.

FDA first approved this application on May 28, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

RANOLAZINE ER 500 MG TABLET

Ranolazine
$0.1649per EA

Strength

500 mg/1

NDC

27241012502

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

RANOLAZINE

Approval Type

Generic (ANDA)

FDA Application

ANDA210054

FDA Approved

5/28/2019

TE Code

AB

On Market Since

8/23/2019

Pharmacological Classes

Anti-anginal
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inhibitors
Organic Cation Transporter 2 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for RANOLAZINE ER 500 MG TABLET has been published 372 times since Aug 21, 2019, and over the history we have for it it has declined 74.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1649 per EA
All-time high$0.6542 (Sep 11, 2019)
All-time low$0.1581 (Jul 22, 2026)
52-week high$0.1691
52-week low$0.1581
Median price$0.2445
Average price$0.2952
Largest weekly change+17.6% (Aug 21, 2024)
Weeks tracked372
Tracking sinceAug 21, 2019

Price History

1W

0.0%

1M

+2.5%

3M

+1.3%

6M

-0.3%

1Y

-2.4%

3Y

-31.3%

5Y

-54.0%

All

-74.8%

Generic Alternatives

The matcher finds 13 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of RANOLAZINE ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 500 MG TABLET, manufactured by Ajanta Pharma USA Inc., is $0.1649 per EA (NDC 27241012502), effective Sep 30, 2026.

How has the price of RANOLAZINE ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for RANOLAZINE ER 500 MG TABLET has declined 74.8%. It has been tracked across 372 weekly CMS publications since Aug 21, 2019.

What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 500 MG TABLET?

Since Aug 21, 2019, the NADAC for RANOLAZINE ER 500 MG TABLET has ranged from a low of $0.1581 (Jul 22, 2026) to a high of $0.6542 (Sep 11, 2019), with a median of $0.2445 per EA.

Are there cheaper alternatives to RANOLAZINE ER 500 MG TABLET?

Yes. 13 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RANOLAZINE ER 500 MG TABLET, is $0.1609 per EA — about 2% below RANOLAZINE ER 500 MG TABLET.

Who manufactures RANOLAZINE ER 500 MG TABLET?

RANOLAZINE ER 500 MG TABLET (NDC 27241012502) is labeled by Ajanta Pharma USA Inc., and CMS classifies it as a generic product.