Product Information
RANOLAZINE ER 500 MG TABLET is a generic product labeled by Lifestar Pharma LLC, priced at $0.1649 per EA under NDC 70756070360. Its NADAC has been published 338 times since Apr 15, 2020.
FDA first approved this application on Feb 12, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Lifestar Pharma LLCNDC
70756070360
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
RANOLAZINEApproval Type
Generic (ANDA)
FDA Application
ANDA212284FDA Approved
2/12/2020
TE Code
AB
On Market Since
4/1/2020
Pharmacological Classes
Price Statistics
The NADAC for RANOLAZINE ER 500 MG TABLET has been published 338 times since Apr 15, 2020, and over the history we have for it it has declined 69.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1649 per EA |
|---|---|
| All-time high | $0.5423 (Apr 15, 2020) |
| All-time low | $0.1581 (Jul 22, 2026) |
| 52-week high | $0.1691 |
| 52-week low | $0.1581 |
| Median price | $0.2355 |
| Average price | $0.2670 |
| Largest weekly change | +17.6% (Aug 21, 2024) |
| Weeks tracked | 338 |
| Tracking since | Apr 15, 2020 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Lifestar Pharma LLC manufacturer profile
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Drug market
Ranolazine market comparison
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Therapeutic class
Anti-anginal class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of RANOLAZINE ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 500 MG TABLET, manufactured by Lifestar Pharma LLC, is $0.1649 per EA (NDC 70756070360), effective Sep 30, 2026.
How has the price of RANOLAZINE ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for RANOLAZINE ER 500 MG TABLET has declined 69.6%. It has been tracked across 338 weekly CMS publications since Apr 15, 2020.
What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 500 MG TABLET?
Since Apr 15, 2020, the NADAC for RANOLAZINE ER 500 MG TABLET has ranged from a low of $0.1581 (Jul 22, 2026) to a high of $0.5423 (Apr 15, 2020), with a median of $0.2355 per EA.
Are there cheaper alternatives to RANOLAZINE ER 500 MG TABLET?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RANOLAZINE ER 500 MG TABLET, is $0.1609 per EA — about 2% below RANOLAZINE ER 500 MG TABLET.
Who manufactures RANOLAZINE ER 500 MG TABLET?
RANOLAZINE ER 500 MG TABLET (NDC 70756070360) is labeled by Lifestar Pharma LLC, and CMS classifies it as a generic product.