Product Information

METFORMIN ER 500 MG OSMOTIC TB is a generic product labeled by Ajanta Pharma USA Inc., priced at $0.1383 per EA under NDC 27241018860. Its NADAC has been published 289 times since Feb 10, 2021.

FDA first approved this application on Apr 9, 2020. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN ER 500 MG OSMOTIC TB

Metformin hydrochloride
$0.1383per EA

Strength

500 mg/1

NDC

27241018860

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA213651

FDA Approved

4/9/2020

TE Code

AB2

On Market Since

4/9/2020

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN ER 500 MG OSMOTIC TB has been published 289 times since Feb 10, 2021, and over the history we have for it it has declined 93.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1383 per EA
All-time high$2.1129 (Apr 14, 2021)
All-time low$0.1017 (Apr 22, 2026)
52-week high$0.1722
52-week low$0.1017
Median price$0.2192
Average price$0.4812
Largest weekly change-77.1% (Feb 22, 2023)
Weeks tracked289
Tracking sinceFeb 10, 2021

Price History

1W

+18.9%

1M

+24.8%

3M

+31.4%

6M

+24.0%

1Y

-5.0%

3Y

-34.4%

5Y

-87.6%

All

-93.5%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 90% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METFORMIN ER 500 MG OSMOTIC TB?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG OSMOTIC TB, manufactured by Ajanta Pharma USA Inc., is $0.1383 per EA (NDC 27241018860), effective Aug 19, 2026.

How has the price of METFORMIN ER 500 MG OSMOTIC TB changed over time?

Over the history we have for it, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has declined 93.5%. It has been tracked across 289 weekly CMS publications since Feb 10, 2021.

What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG OSMOTIC TB?

Since Feb 10, 2021, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has ranged from a low of $0.1017 (Apr 22, 2026) to a high of $2.1129 (Apr 14, 2021), with a median of $0.2192 per EA.

Are there cheaper alternatives to METFORMIN ER 500 MG OSMOTIC TB?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0142 per EA — about 90% below METFORMIN ER 500 MG OSMOTIC TB.

Who manufactures METFORMIN ER 500 MG OSMOTIC TB?

METFORMIN ER 500 MG OSMOTIC TB (NDC 27241018860) is labeled by Ajanta Pharma USA Inc., and CMS classifies it as a generic product.