Product Information

HISTEX-DM SYRUP is a generic product labeled by Allegis Pharmaceuticals, LLC, priced at $0.0749 per ML under NDC 28595080416. Its NADAC has been published 142 times since Jan 17, 2018.

OTC

Strength

20; 10; 2.5 mg/5mL; mg/5mL; mg/5mL

NDC

28595080416

Classification

Generic

Dosage Form

SYRUP

Route

ORAL

Effective Date

9/23/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

3/19/2014

Pharmacological Classes

Adrenergic alpha1-Agonists
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists
alpha-1 Adrenergic Agonist

Price Statistics

The NADAC for HISTEX-DM SYRUP has been published 142 times since Jan 17, 2018, and over the history we have for it it has risen 6.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0749 per ML
All-time high$0.0749 (Sep 30, 2026)
All-time low$0.0703 (Jan 17, 2018)
52-week high$0.0749
52-week low$0.0712
Median price$0.0712
Average price$0.0713
Largest weekly change+3.4% (May 20, 2026)
Weeks tracked142
Tracking sinceJan 17, 2018

Price History

1W

0.0%

1M

+1.4%

3M

+1.4%

6M

+4.8%

1Y

+5.2%

3Y

+6.6%

5Y

+6.6%

All

+6.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of HISTEX-DM SYRUP?

The current National Average Drug Acquisition Cost (NADAC) for HISTEX-DM SYRUP, manufactured by Allegis Pharmaceuticals, LLC, is $0.0749 per ML (NDC 28595080416), effective Sep 30, 2026.

How has the price of HISTEX-DM SYRUP changed over time?

Over the history we have for it, the NADAC for HISTEX-DM SYRUP has risen 6.6%. It has been tracked across 142 weekly CMS publications since Jan 17, 2018.

What are the highest and lowest recorded NADAC prices for HISTEX-DM SYRUP?

Since Jan 17, 2018, the NADAC for HISTEX-DM SYRUP has ranged from a low of $0.0703 (Jan 17, 2018) to a high of $0.0749 (Sep 30, 2026), with a median of $0.0712 per ML.

Are there cheaper alternatives to HISTEX-DM SYRUP?

No other NADAC-published product currently shares the active ingredient and strength of HISTEX-DM SYRUP in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures HISTEX-DM SYRUP?

HISTEX-DM SYRUP (NDC 28595080416) is labeled by Allegis Pharmaceuticals, LLC, and CMS classifies it as a generic product.