Product Information
METFORMIN HCL ER 500 MG TABLET is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.0284 per EA under NDC 29300038905. Its NADAC has been published 266 times since Sep 1, 2021.
FDA first approved this application on Aug 11, 2021. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Unichem Pharmaceuticals (USA) Inc.NDC
29300038905
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA213359FDA Approved
8/11/2021
TE Code
AB1
On Market Since
8/11/2021
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL ER 500 MG TABLET has been published 266 times since Sep 1, 2021, and over the history we have for it it has declined 23.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0284 per EA |
|---|---|
| All-time high | $0.0445 (Nov 16, 2022) |
| All-time low | $0.0238 (Nov 20, 2024) |
| 52-week high | $0.0299 |
| 52-week low | $0.0284 |
| Median price | $0.0313 |
| Average price | $0.0324 |
| Largest weekly change | +29.1% (Feb 22, 2023) |
| Weeks tracked | 266 |
| Tracking since | Sep 1, 2021 |
Generic Alternatives
The matcher finds 21 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 49% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Unichem Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Metformin Hydrochloride market comparison
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Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METFORMIN HCL ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL ER 500 MG TABLET, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.0284 per EA (NDC 29300038905), effective Sep 30, 2026.
How has the price of METFORMIN HCL ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL ER 500 MG TABLET has declined 23.6%. It has been tracked across 266 weekly CMS publications since Sep 1, 2021.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL ER 500 MG TABLET?
Since Sep 1, 2021, the NADAC for METFORMIN HCL ER 500 MG TABLET has ranged from a low of $0.0238 (Nov 20, 2024) to a high of $0.0445 (Nov 16, 2022), with a median of $0.0313 per EA.
Are there cheaper alternatives to METFORMIN HCL ER 500 MG TABLET?
Yes. 21 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0145 per EA — about 49% below METFORMIN HCL ER 500 MG TABLET.
Who manufactures METFORMIN HCL ER 500 MG TABLET?
METFORMIN HCL ER 500 MG TABLET (NDC 29300038905) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.