Product Information
GUANFACINE HCL ER 4 MG TABLET is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.1783 per EA under NDC 29300046301. Its NADAC has been published 50 times since Sep 10, 2025.
FDA first approved this application on Nov 19, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4 mg/1
Manufacturer
Unichem Pharmaceuticals (USA) Inc.NDC
29300046301
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA219033FDA Approved
11/19/2024
TE Code
AB
On Market Since
11/19/2024
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 4 MG TABLET has been published 50 times since Sep 10, 2025, and over the history we have for it it has declined 19.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1783 per EA |
|---|---|
| All-time high | $0.2218 (Sep 10, 2025) |
| All-time low | $0.1681 (Apr 22, 2026) |
| 52-week high | $0.2218 |
| 52-week low | $0.1681 |
| Median price | $0.1924 |
| Average price | $0.1915 |
| Largest weekly change | -9.8% (Mar 18, 2026) |
| Weeks tracked | 50 |
| Tracking since | Sep 10, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 4 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 4 MG TABLET, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.1783 per EA (NDC 29300046301), effective Aug 19, 2026.
How has the price of GUANFACINE HCL ER 4 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 4 MG TABLET has declined 19.6%. It has been tracked across 50 weekly CMS publications since Sep 10, 2025.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 4 MG TABLET?
Since Sep 10, 2025, the NADAC for GUANFACINE HCL ER 4 MG TABLET has ranged from a low of $0.1681 (Apr 22, 2026) to a high of $0.2218 (Sep 10, 2025), with a median of $0.1924 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 4 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as GUANFACINE HCL ER 4 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures GUANFACINE HCL ER 4 MG TABLET?
GUANFACINE HCL ER 4 MG TABLET (NDC 29300046301) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.