Product Information
GUANFACINE HCL ER 4 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $0.2043 per EA under NDC 16714019301. Its NADAC has been published 178 times since Jun 8, 2022.
FDA first approved this application on Nov 16, 2017.
Strength
4 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714019301
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
10/22/2025
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205689FDA Approved
11/16/2017
On Market Since
9/17/2021
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 4 MG TABLET has been published 178 times since Jun 8, 2022, and over the history we have for it it has declined 17.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2043 per EA |
|---|---|
| All-time high | $0.2844 (Dec 13, 2023) |
| All-time low | $0.1661 (Nov 20, 2024) |
| 52-week high | $0.2218 |
| 52-week low | $0.2043 |
| Median price | $0.2237 |
| Average price | $0.2243 |
| Largest weekly change | +27.1% (Nov 22, 2023) |
| Weeks tracked | 178 |
| Tracking since | Jun 8, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-7.9%
3Y
-21.2%
5Y
N/A
All
-17.9%
Last surveyed Oct 29, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 13% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 4 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 4 MG TABLET, manufactured by NorthStar Rx LLC, is $0.2043 per EA (NDC 16714019301), effective Oct 29, 2025.
How has the price of GUANFACINE HCL ER 4 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 4 MG TABLET has declined 17.9%. It has been tracked across 178 weekly CMS publications since Jun 8, 2022.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 4 MG TABLET?
Since Jun 8, 2022, the NADAC for GUANFACINE HCL ER 4 MG TABLET has ranged from a low of $0.1661 (Nov 20, 2024) to a high of $0.2844 (Dec 13, 2023), with a median of $0.2237 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 4 MG TABLET?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 4 MG TABLET, is $0.1783 per EA — about 13% below GUANFACINE HCL ER 4 MG TABLET.
Who manufactures GUANFACINE HCL ER 4 MG TABLET?
GUANFACINE HCL ER 4 MG TABLET (NDC 16714019301) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.