Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.0783 per EA under NDC 33342005207. Its NADAC has been published 252 times since Oct 27, 2021.

FDA first approved this application on Aug 9, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB

Losartan potassium and Hydrochlorothiazide
$0.0783per EA

Strength

25; 100 mg/1; mg/1

NDC

33342005207

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202289

FDA Approved

8/9/2012

TE Code

AB

On Market Since

5/3/2012

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has been published 252 times since Oct 27, 2021, and over the history we have for it it has declined 54.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0783 per EA
All-time high$0.2811 (May 11, 2022)
All-time low$0.0771 (Jul 22, 2026)
52-week high$0.0876
52-week low$0.0771
Median price$0.1245
Average price$0.1235
Largest weekly change+33.4% (Apr 20, 2022)
Weeks tracked252
Tracking sinceOct 27, 2021

Price History

1W

+1.6%

1M

+1.6%

3M

-3.4%

6M

-3.5%

1Y

-7.6%

3Y

-37.2%

5Y

N/A

All

-54.0%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB, manufactured by Macleods Pharmaceuticals Limited, is $0.0783 per EA (NDC 33342005207), effective Aug 19, 2026.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has declined 54.0%. It has been tracked across 252 weekly CMS publications since Oct 27, 2021.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?

Since Oct 27, 2021, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has ranged from a low of $0.0771 (Jul 22, 2026) to a high of $0.2811 (May 11, 2022), with a median of $0.1245 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB (NDC 33342005207) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.