Product Information

PIOGLITAZONE-METFORMIN 15-500 is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.3220 per EA under NDC 33342017609. Its NADAC has been published 480 times since Jun 14, 2017.

FDA first approved this application on Nov 5, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PIOGLITAZONE-METFORMIN 15-500

Pioglitazone and metformin hydrochloride
$0.3220per EA

Strength

500; 15 mg/1; mg/1

NDC

33342017609

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA204802

FDA Approved

11/5/2015

TE Code

AB

On Market Since

11/6/2015

Pharmacological Classes

Biguanide
Biguanides
Peroxisome Proliferator Receptor alpha Agonist
Peroxisome Proliferator Receptor gamma Agonist
Peroxisome Proliferator-activated Receptor alpha Agonists
Peroxisome Proliferator-activated Receptor gamma Agonists
Thiazolidinedione
Thiazolidinediones

Price Statistics

The NADAC for PIOGLITAZONE-METFORMIN 15-500 has been published 480 times since Jun 14, 2017, and over the history we have for it it has declined 75.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3220 per EA
All-time high$1.3288 (Jul 12, 2017)
All-time low$0.1994 (Apr 19, 2023)
52-week high$0.5670
52-week low$0.3220
Median price$0.6178
Average price$0.6444
Largest weekly change+79.1% (Apr 17, 2024)
Weeks tracked480
Tracking sinceJun 14, 2017

Price History

1W

-14.5%

1M

-14.5%

3M

-21.5%

6M

-14.5%

1Y

-43.2%

3Y

-17.9%

5Y

-49.1%

All

-75.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PIOGLITAZONE-METFORMIN 15-500?

The current National Average Drug Acquisition Cost (NADAC) for PIOGLITAZONE-METFORMIN 15-500, manufactured by Macleods Pharmaceuticals Limited, is $0.3220 per EA (NDC 33342017609), effective Aug 19, 2026.

How has the price of PIOGLITAZONE-METFORMIN 15-500 changed over time?

Over the history we have for it, the NADAC for PIOGLITAZONE-METFORMIN 15-500 has declined 75.6%. It has been tracked across 480 weekly CMS publications since Jun 14, 2017.

What are the highest and lowest recorded NADAC prices for PIOGLITAZONE-METFORMIN 15-500?

Since Jun 14, 2017, the NADAC for PIOGLITAZONE-METFORMIN 15-500 has ranged from a low of $0.1994 (Apr 19, 2023) to a high of $1.3288 (Jul 12, 2017), with a median of $0.6178 per EA.

Are there cheaper alternatives to PIOGLITAZONE-METFORMIN 15-500?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PIOGLITAZONE-METFORMIN 15-500 in a comparable dosage form, but none are currently priced below it.

Who manufactures PIOGLITAZONE-METFORMIN 15-500?

PIOGLITAZONE-METFORMIN 15-500 (NDC 33342017609) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.