Product Information
CLOBETASOL 0.05% OINTMENT is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.1083 per GM under NDC 33342050645. Its NADAC has been published 101 times since Oct 30, 2024.
FDA first approved this application on Dec 28, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342050645
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA215990FDA Approved
12/28/2023
TE Code
AB
On Market Since
12/28/2023
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% OINTMENT has been published 101 times since Oct 30, 2024, and over the history we have for it it has declined 35.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1083 per GM |
|---|---|
| All-time high | $0.1938 (Apr 16, 2025) |
| All-time low | $0.0961 (Nov 20, 2024) |
| 52-week high | $0.1654 |
| 52-week low | $0.1033 |
| Median price | $0.1380 |
| Average price | $0.1416 |
| Largest weekly change | -43.0% (Nov 20, 2024) |
| Weeks tracked | 101 |
| Tracking since | Oct 30, 2024 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Macleods Pharmaceuticals Limited manufacturer profile
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Drug market
Clobetasol Propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% OINTMENT, manufactured by Macleods Pharmaceuticals Limited, is $0.1083 per GM (NDC 33342050645), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% OINTMENT changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% OINTMENT has declined 35.7%. It has been tracked across 101 weekly CMS publications since Oct 30, 2024.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% OINTMENT?
Since Oct 30, 2024, the NADAC for CLOBETASOL 0.05% OINTMENT has ranged from a low of $0.0961 (Nov 20, 2024) to a high of $0.1938 (Apr 16, 2025), with a median of $0.1380 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% OINTMENT?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CLOBETASOL 0.05% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures CLOBETASOL 0.05% OINTMENT?
CLOBETASOL 0.05% OINTMENT (NDC 33342050645) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.