Product Information
METFORMIN HCL 500 MG TABLET is a generic product labeled by Laurus Labs Limited, priced at $0.0145 per EA under NDC 42385094705. Its NADAC has been published 191 times since Feb 8, 2023.
FDA first approved this application on Aug 27, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Laurus Labs LimitedNDC
42385094705
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA209882FDA Approved
8/27/2018
TE Code
AB
On Market Since
5/17/2021
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL 500 MG TABLET has been published 191 times since Feb 8, 2023, and over the history we have for it it has declined 11.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0145 per EA |
|---|---|
| All-time high | $0.0168 (Dec 13, 2023) |
| All-time low | $0.0123 (Nov 20, 2024) |
| 52-week high | $0.0147 |
| 52-week low | $0.0139 |
| Median price | $0.0144 |
| Average price | $0.0147 |
| Largest weekly change | +20.4% (Jun 19, 2024) |
| Weeks tracked | 191 |
| Tracking since | Feb 8, 2023 |
Generic Alternatives
The matcher finds 21 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Laurus Labs Limited manufacturer profile
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Drug market
Metformin Hydrochloride market comparison
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Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METFORMIN HCL 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL 500 MG TABLET, manufactured by Laurus Labs Limited, is $0.0145 per EA (NDC 42385094705), effective Sep 30, 2026.
How has the price of METFORMIN HCL 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL 500 MG TABLET has declined 11.8%. It has been tracked across 191 weekly CMS publications since Feb 8, 2023.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL 500 MG TABLET?
Since Feb 8, 2023, the NADAC for METFORMIN HCL 500 MG TABLET has ranged from a low of $0.0123 (Nov 20, 2024) to a high of $0.0168 (Dec 13, 2023), with a median of $0.0144 per EA.
Are there cheaper alternatives to METFORMIN HCL 500 MG TABLET?
21 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METFORMIN HCL 500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METFORMIN HCL 500 MG TABLET?
METFORMIN HCL 500 MG TABLET (NDC 42385094705) is labeled by Laurus Labs Limited, and CMS classifies it as a generic product.