Product Information
PROTRIPTYLINE HCL 10 MG TABLET is a generic product labeled by Sigmapharm Laboratories LLC, priced at $2.7121 per EA under NDC 42794000702. Its NADAC has been published 326 times since May 27, 2020.
FDA first approved this application on May 3, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/1
Manufacturer
Sigmapharm Laboratories LLCNDC
42794000702
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROTRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090462FDA Approved
5/3/2010
TE Code
AB
On Market Since
3/2/2020
Pharmacological Classes
Price Statistics
The NADAC for PROTRIPTYLINE HCL 10 MG TABLET has been published 326 times since May 27, 2020, and over the history we have for it it has declined 15.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.7121 per EA |
|---|---|
| All-time high | $3.4886 (Jan 12, 2022) |
| All-time low | $2.0871 (Dec 23, 2020) |
| 52-week high | $3.1775 |
| 52-week low | $2.6976 |
| Median price | $2.8929 |
| Average price | $2.8643 |
| Largest weekly change | +47.4% (Jan 20, 2021) |
| Weeks tracked | 326 |
| Tracking since | May 27, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROTRIPTYLINE HCL 10 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROTRIPTYLINE HCL 10 MG TABLET, manufactured by Sigmapharm Laboratories LLC, is $2.7121 per EA (NDC 42794000702), effective Aug 19, 2026.
How has the price of PROTRIPTYLINE HCL 10 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROTRIPTYLINE HCL 10 MG TABLET has declined 15.7%. It has been tracked across 326 weekly CMS publications since May 27, 2020.
What are the highest and lowest recorded NADAC prices for PROTRIPTYLINE HCL 10 MG TABLET?
Since May 27, 2020, the NADAC for PROTRIPTYLINE HCL 10 MG TABLET has ranged from a low of $2.0871 (Dec 23, 2020) to a high of $3.4886 (Jan 12, 2022), with a median of $2.8929 per EA.
Are there cheaper alternatives to PROTRIPTYLINE HCL 10 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROTRIPTYLINE HCL 10 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROTRIPTYLINE HCL 10 MG TABLET?
PROTRIPTYLINE HCL 10 MG TABLET (NDC 42794000702) is labeled by Sigmapharm Laboratories LLC, and CMS classifies it as a generic product.