Product Information

LIOTHYRONINE SOD 25 MCG TAB is a generic product labeled by Sigmapharm Laboratories LLC, priced at $0.3217 per EA under NDC 42794001912. Its NADAC has been published 423 times since Jul 18, 2018.

FDA first approved this application on Nov 29, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the Liothyronine Sodium market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

LIOTHYRONINE SOD 25 MCG TAB

Liothyronine Sodium
$0.3217per EA
Low Outlier

Strength

25 ug/1

NDC

42794001912

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LIOTHYRONINE SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA200295

FDA Approved

11/29/2012

TE Code

AB

On Market Since

12/3/2012

Pharmacological Classes

Triiodothyronine
l-Triiodothyronine

Price Statistics

The NADAC for LIOTHYRONINE SOD 25 MCG TAB has been published 423 times since Jul 18, 2018, and over the history we have for it it has declined 70.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3217 per EA
All-time high$1.1453 (Sep 12, 2018)
All-time low$0.2458 (Nov 20, 2024)
52-week high$0.3674
52-week low$0.3001
Median price$0.4841
Average price$0.5434
Largest weekly change+50.4% (Jun 19, 2024)
Weeks tracked423
Tracking sinceJul 18, 2018

Price History

1W

+0.6%

1M

+0.6%

3M

+2.8%

6M

+3.2%

1Y

-12.5%

3Y

-16.0%

5Y

-39.3%

All

-70.4%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LIOTHYRONINE SOD 25 MCG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LIOTHYRONINE SOD 25 MCG TAB, manufactured by Sigmapharm Laboratories LLC, is $0.3217 per EA (NDC 42794001912), effective Aug 19, 2026.

How has the price of LIOTHYRONINE SOD 25 MCG TAB changed over time?

Over the history we have for it, the NADAC for LIOTHYRONINE SOD 25 MCG TAB has declined 70.4%. It has been tracked across 423 weekly CMS publications since Jul 18, 2018.

What are the highest and lowest recorded NADAC prices for LIOTHYRONINE SOD 25 MCG TAB?

Since Jul 18, 2018, the NADAC for LIOTHYRONINE SOD 25 MCG TAB has ranged from a low of $0.2458 (Nov 20, 2024) to a high of $1.1453 (Sep 12, 2018), with a median of $0.4841 per EA.

Are there cheaper alternatives to LIOTHYRONINE SOD 25 MCG TAB?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIOTHYRONINE SOD 25 MCG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures LIOTHYRONINE SOD 25 MCG TAB?

LIOTHYRONINE SOD 25 MCG TAB (NDC 42794001912) is labeled by Sigmapharm Laboratories LLC, and CMS classifies it as a generic product.