Product Information
LIOTHYRONINE SOD 50 MCG TAB is a generic product labeled by Sigmapharm Laboratories LLC, priced at $0.3622 per EA under NDC 42794002002. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Nov 29, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Liothyronine Sodium market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 ug/1
Manufacturer
Sigmapharm Laboratories LLCNDC
42794002002
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LIOTHYRONINE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA200295FDA Approved
11/29/2012
TE Code
AB
On Market Since
12/3/2012
Pharmacological Classes
Price Statistics
The NADAC for LIOTHYRONINE SOD 50 MCG TAB has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 63.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3622 per EA |
|---|---|
| All-time high | $1.7017 (Jun 13, 2018) |
| All-time low | $0.3361 (May 20, 2026) |
| 52-week high | $0.4689 |
| 52-week low | $0.3361 |
| Median price | $0.9106 |
| Average price | $0.8524 |
| Largest weekly change | +104.7% (May 23, 2018) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Sigmapharm Laboratories LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Liothyronine Sodium market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
l-Triiodothyronine class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIOTHYRONINE SOD 50 MCG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LIOTHYRONINE SOD 50 MCG TAB, manufactured by Sigmapharm Laboratories LLC, is $0.3622 per EA (NDC 42794002002), effective Sep 30, 2026.
How has the price of LIOTHYRONINE SOD 50 MCG TAB changed over time?
Over the history we have for it, the NADAC for LIOTHYRONINE SOD 50 MCG TAB has declined 63.8%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LIOTHYRONINE SOD 50 MCG TAB?
Since Nov 28, 2013, the NADAC for LIOTHYRONINE SOD 50 MCG TAB has ranged from a low of $0.3361 (May 20, 2026) to a high of $1.7017 (Jun 13, 2018), with a median of $0.9106 per EA.
Are there cheaper alternatives to LIOTHYRONINE SOD 50 MCG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIOTHYRONINE SOD 50 MCG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LIOTHYRONINE SOD 50 MCG TAB?
LIOTHYRONINE SOD 50 MCG TAB (NDC 42794002002) is labeled by Sigmapharm Laboratories LLC, and CMS classifies it as a generic product.