Product Information
HYDROXYZINE HCL 50 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0583 per EA under NDC 42806016105. Its NADAC has been published 585 times since Jun 10, 2015.
FDA first approved this application on Dec 28, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Epic Pharma LLCNDC
42806016105
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROXYZINE DIHYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040604FDA Approved
12/28/2004
TE Code
AB
On Market Since
3/31/2015
Pharmacological Classes
Price Statistics
The NADAC for HYDROXYZINE HCL 50 MG TABLET has been published 585 times since Jun 10, 2015, and over the history we have for it it has declined 51.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0583 per EA |
|---|---|
| All-time high | $0.1428 (Feb 10, 2016) |
| All-time low | $0.0489 (Nov 20, 2024) |
| 52-week high | $0.0663 |
| 52-week low | $0.0583 |
| Median price | $0.0847 |
| Average price | $0.0860 |
| Largest weekly change | +36.0% (Jan 19, 2022) |
| Weeks tracked | 585 |
| Tracking since | Jun 10, 2015 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROXYZINE HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROXYZINE HCL 50 MG TABLET, manufactured by Epic Pharma LLC, is $0.0583 per EA (NDC 42806016105), effective Aug 19, 2026.
How has the price of HYDROXYZINE HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROXYZINE HCL 50 MG TABLET has declined 51.2%. It has been tracked across 585 weekly CMS publications since Jun 10, 2015.
What are the highest and lowest recorded NADAC prices for HYDROXYZINE HCL 50 MG TABLET?
Since Jun 10, 2015, the NADAC for HYDROXYZINE HCL 50 MG TABLET has ranged from a low of $0.0489 (Nov 20, 2024) to a high of $0.1428 (Feb 10, 2016), with a median of $0.0847 per EA.
Are there cheaper alternatives to HYDROXYZINE HCL 50 MG TABLET?
Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROXYZINE HCL 50 MG TABLET, is $0.0560 per EA — about 4% below HYDROXYZINE HCL 50 MG TABLET.
Who manufactures HYDROXYZINE HCL 50 MG TABLET?
HYDROXYZINE HCL 50 MG TABLET (NDC 42806016105) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.