Product Information
HYDROXYZINE HCL 50 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0583 per EA under NDC 00904661861. Its NADAC has been published 401 times since Dec 19, 2018.
FDA first approved this application on Dec 28, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904661861
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROXYZINE DIHYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040604FDA Approved
12/28/2004
TE Code
AB
On Market Since
3/31/2015
Pharmacological Classes
Price Statistics
The NADAC for HYDROXYZINE HCL 50 MG TABLET has been published 401 times since Dec 19, 2018, and over the history we have for it it has declined 31.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0583 per EA |
|---|---|
| All-time high | $0.1000 (Jan 15, 2020) |
| All-time low | $0.0489 (Nov 20, 2024) |
| 52-week high | $0.0663 |
| 52-week low | $0.0583 |
| Median price | $0.0751 |
| Average price | $0.0762 |
| Largest weekly change | +36.0% (Jan 19, 2022) |
| Weeks tracked | 401 |
| Tracking since | Dec 19, 2018 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROXYZINE HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROXYZINE HCL 50 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0583 per EA (NDC 00904661861), effective Aug 19, 2026.
How has the price of HYDROXYZINE HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROXYZINE HCL 50 MG TABLET has declined 31.9%. It has been tracked across 401 weekly CMS publications since Dec 19, 2018.
What are the highest and lowest recorded NADAC prices for HYDROXYZINE HCL 50 MG TABLET?
Since Dec 19, 2018, the NADAC for HYDROXYZINE HCL 50 MG TABLET has ranged from a low of $0.0489 (Nov 20, 2024) to a high of $0.1000 (Jan 15, 2020), with a median of $0.0751 per EA.
Are there cheaper alternatives to HYDROXYZINE HCL 50 MG TABLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROXYZINE HCL 50 MG TABLET, is $0.0560 per EA — about 4% below HYDROXYZINE HCL 50 MG TABLET.
Who manufactures HYDROXYZINE HCL 50 MG TABLET?
HYDROXYZINE HCL 50 MG TABLET (NDC 00904661861) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.