Product Information
DOXYCYCLINE HYCLATE 100 MG TAB is a generic product labeled by Epic Pharma LLC, priced at $0.1129 per EA under NDC 42806031050. Its NADAC has been published 58 times since Jul 16, 2025.
FDA first approved this application on Nov 8, 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Epic Pharma LLCNDC
42806031050
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DOXYCYCLINE HYCLATEApproval Type
Generic (ANDA)
FDA Application
ANDA062269FDA Approved
11/8/1982
TE Code
AB
On Market Since
3/7/2025
Pharmacological Classes
Price Statistics
The NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has been published 58 times since Jul 16, 2025, and over the history we have for it it has declined 10.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1129 per EA |
|---|---|
| All-time high | $0.1262 (Jul 16, 2025) |
| All-time low | $0.1129 (Aug 19, 2026) |
| 52-week high | $0.1241 |
| 52-week low | $0.1129 |
| Median price | $0.1206 |
| Average price | $0.1202 |
| Largest weekly change | -5.1% (Jun 17, 2026) |
| Weeks tracked | 58 |
| Tracking since | Jul 16, 2025 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DOXYCYCLINE HYCLATE 100 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE HYCLATE 100 MG TAB, manufactured by Epic Pharma LLC, is $0.1129 per EA (NDC 42806031050), effective Aug 19, 2026.
How has the price of DOXYCYCLINE HYCLATE 100 MG TAB changed over time?
Over the history we have for it, the NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has declined 10.5%. It has been tracked across 58 weekly CMS publications since Jul 16, 2025.
What are the highest and lowest recorded NADAC prices for DOXYCYCLINE HYCLATE 100 MG TAB?
Since Jul 16, 2025, the NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has ranged from a low of $0.1129 (Aug 19, 2026) to a high of $0.1262 (Jul 16, 2025), with a median of $0.1206 per EA.
Are there cheaper alternatives to DOXYCYCLINE HYCLATE 100 MG TAB?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DOXYCYCLINE HYCLATE 100 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXYCYCLINE HYCLATE 100 MG TAB?
DOXYCYCLINE HYCLATE 100 MG TAB (NDC 42806031050) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.