Product Information

METFORMIN ER 500 MG OSMOTIC TB is a generic product labeled by Epic Pharma LLC, priced at $0.1383 per EA under NDC 42806040560. Its NADAC has been published 377 times since Jun 5, 2019.

FDA first approved this application on Dec 27, 2018. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN ER 500 MG OSMOTIC TB

metformin hydrochloride tablets
$0.1383per EA

Strength

500 mg/1

Manufacturer

Epic Pharma LLC

NDC

42806040560

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA209993

FDA Approved

12/27/2018

TE Code

AB2

On Market Since

1/4/2019

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN ER 500 MG OSMOTIC TB has been published 377 times since Jun 5, 2019, and over the history we have for it it has declined 95.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1383 per EA
All-time high$3.0540 (Jun 12, 2019)
All-time low$0.1017 (Apr 22, 2026)
52-week high$0.1722
52-week low$0.1017
Median price$0.4584
Average price$0.8966
Largest weekly change-77.1% (Feb 22, 2023)
Weeks tracked377
Tracking sinceJun 5, 2019

Price History

1W

+18.9%

1M

+18.9%

3M

+31.4%

6M

+24.0%

1Y

-5.0%

3Y

-34.4%

5Y

-87.6%

All

-95.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the metformin hydrochloride tablets market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of METFORMIN ER 500 MG OSMOTIC TB?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG OSMOTIC TB, manufactured by Epic Pharma LLC, is $0.1383 per EA (NDC 42806040560), effective Aug 19, 2026.

How has the price of METFORMIN ER 500 MG OSMOTIC TB changed over time?

Over the history we have for it, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has declined 95.5%. It has been tracked across 377 weekly CMS publications since Jun 5, 2019.

What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG OSMOTIC TB?

Since Jun 5, 2019, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has ranged from a low of $0.1017 (Apr 22, 2026) to a high of $3.0540 (Jun 12, 2019), with a median of $0.4584 per EA.

Are there cheaper alternatives to METFORMIN ER 500 MG OSMOTIC TB?

No other NADAC-published product currently shares the active ingredient and strength of METFORMIN ER 500 MG OSMOTIC TB in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures METFORMIN ER 500 MG OSMOTIC TB?

METFORMIN ER 500 MG OSMOTIC TB (NDC 42806040560) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.