This NDC is on FDA's drug shortage list (posted Jul 14, 2023)
Reported reason: Shortage of an active ingredient
Product Information
LISDEXAMFETAMINE 40 MG CAPSULE is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $2.6298 per EA under NDC 42858016401. Its NADAC has been published 122 times since Apr 24, 2024.
FDA first approved this application on Aug 25, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858016401
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LISDEXAMFETAMINE DIMESYLATEApproval Type
Generic (ANDA)
FDA Application
ANDA215330FDA Approved
8/25/2023
TE Code
AB
On Market Since
1/30/2024
Pharmacological Classes
Price Statistics
The NADAC for LISDEXAMFETAMINE 40 MG CAPSULE has been published 122 times since Apr 24, 2024, and over the history we have for it it has declined 47.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.6298 per EA |
|---|---|
| All-time high | $5.1573 (Jul 10, 2024) |
| All-time low | $2.6298 (Aug 19, 2026) |
| 52-week high | $3.7294 |
| 52-week low | $2.6298 |
| Median price | $3.9747 |
| Average price | $3.8977 |
| Largest weekly change | +34.4% (Jun 19, 2024) |
| Weeks tracked | 122 |
| Tracking since | Apr 24, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LISDEXAMFETAMINE 40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for LISDEXAMFETAMINE 40 MG CAPSULE, manufactured by Rhodes Pharmaceuticals L.P., is $2.6298 per EA (NDC 42858016401), effective Aug 19, 2026.
How has the price of LISDEXAMFETAMINE 40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for LISDEXAMFETAMINE 40 MG CAPSULE has declined 47.9%. It has been tracked across 122 weekly CMS publications since Apr 24, 2024.
What are the highest and lowest recorded NADAC prices for LISDEXAMFETAMINE 40 MG CAPSULE?
Since Apr 24, 2024, the NADAC for LISDEXAMFETAMINE 40 MG CAPSULE has ranged from a low of $2.6298 (Aug 19, 2026) to a high of $5.1573 (Jul 10, 2024), with a median of $3.9747 per EA.
Are there cheaper alternatives to LISDEXAMFETAMINE 40 MG CAPSULE?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LISDEXAMFETAMINE 40 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures LISDEXAMFETAMINE 40 MG CAPSULE?
LISDEXAMFETAMINE 40 MG CAPSULE (NDC 42858016401) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.
Is LISDEXAMFETAMINE 40 MG CAPSULE in shortage?
Yes — NDC 42858016401 is currently listed in FDA's drug shortage database (posted Jul 14, 2023). Reported reason: Shortage of an active ingredient.