Back to Market Feed

Product Information

MIGRAINE 250-250-65 MG CPLT is a generic product labeled by AmerisourceBergen, priced at $0.0649 per EA under NDC 24385036571. Its NADAC has been published 550 times since Feb 10, 2016.

FDA first approved this application on Nov 26, 2001.

MIGRAINE 250-250-65 MG CPLT

Acetaminophen, Aspirin, Caffeine
$0.0649per EA
OTC

Strength

250; 250; 65 mg/1; mg/1; mg/1

Manufacturer

AmerisourceBergen

NDC

24385036571

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA075794

FDA Approved

11/26/2001

On Market Since

5/13/2002

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Central Nervous System Stimulant
Central Nervous System Stimulation
Cyclooxygenase Inhibitors
Decreased Platelet Aggregation
Decreased Prostaglandin Production
Methylxanthine
Nonsteroidal Anti-inflammatory Drug
Platelet Aggregation Inhibitor
Xanthines

Price Statistics

The NADAC for MIGRAINE 250-250-65 MG CPLT has been published 550 times since Feb 10, 2016, and over the history we have for it it has risen 14.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0649 per EA
All-time high$0.0698 (Sep 11, 2024)
All-time low$0.0359 (May 18, 2016)
52-week high$0.0691
52-week low$0.0635
Median price$0.0572
Average price$0.0576
Largest weekly change+34.6% (Jul 20, 2016)
Weeks tracked550
Tracking sinceFeb 10, 2016

Price History

1W

-2.6%

1M

-2.6%

3M

-3.3%

6M

+1.9%

1Y

-5.4%

3Y

+9.6%

5Y

+8.9%

All

+14.3%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

6 alternatives • Same active ingredient

MIGRAINE FORMULA CAPLET
Generic
24385036578•AmerisourceBergen
$0.0649
HEADACHE RLF 250-250-65 MG CPLT
Generic
70000006601•Cardinal Health
$0.0649
GS MIGRAINE 250-250-65 MG CPLT
Generic
00113037478•L. Perrigo Company
$0.0649
PAIN RELIEVER PLS 250-250-65 MG
Generic
00536132601•Rugby Laboratories
$0.0649
FT MIGRAINE 250-250-65 MG CPLT
Generic
70677113301•Strategic Sourcing Services LLC
$0.0649
QC HEADACHE 250-250-65 MG TAB
Generic
83324006324•Chain Drug Marketing Association
$0.0672
+3% more

Related Drugs

Same classification

MINIPRIN EC 81 MG TABLET
Generic
49483033010•Time-Cap Labs Inc.
$0.0118
per EA
MINIPRIN EC 81 MG TABLET
Generic
49483033012•Time-Cap Labs Inc.
$0.0118
per EA
QC ASPIRIN 325 MG TABLET
Generic
63868035203•Chain Drug Marketing Association
$0.0121
per EA
QC ASPIRIN 325 MG TABLET
Generic
63868035210•Chain Drug Marketing Association
$0.0121
per EA
ST. JOSEPH ASPIRIN EC 81 MG TB
Generic
69536018112•Foundation Consumer Healthcare LLC
$0.0139
per EA
ASPIRIN EC 81 MG TABLET
Generic
00536123441•Rugby Laboratories
$0.0146
per EA
ASPIRIN EC 81 MG TABLET
Generic
00904675180•Major Pharmaceuticals
$0.0146
per EA
ASPIRIN EC 81 MG TABLET
Generic
00904678370•Major Pharmaceuticals
$0.0146
per EA
GNP ASPIRIN EC 81 MG TABLET
Generic
46122059848•AmerisourceBergen
$0.0146
per EA
GNP ASPIRIN EC 81 MG TABLET
Generic
46122059887•AmerisourceBergen
$0.0146
per EA

Frequently asked questions

What is the NADAC price of MIGRAINE 250-250-65 MG CPLT?

The current National Average Drug Acquisition Cost (NADAC) for MIGRAINE 250-250-65 MG CPLT, manufactured by AmerisourceBergen, is $0.0649 per EA (NDC 24385036571), effective Aug 19, 2026.

How has the price of MIGRAINE 250-250-65 MG CPLT changed over time?

Over the history we have for it, the NADAC for MIGRAINE 250-250-65 MG CPLT has risen 14.3%. It has been tracked across 550 weekly CMS publications since Feb 10, 2016.

What are the highest and lowest recorded NADAC prices for MIGRAINE 250-250-65 MG CPLT?

Since Feb 10, 2016, the NADAC for MIGRAINE 250-250-65 MG CPLT has ranged from a low of $0.0359 (May 18, 2016) to a high of $0.0698 (Sep 11, 2024), with a median of $0.0572 per EA.

Are there cheaper alternatives to MIGRAINE 250-250-65 MG CPLT?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIGRAINE 250-250-65 MG CPLT in a comparable dosage form, but none are currently priced below it.

Who manufactures MIGRAINE 250-250-65 MG CPLT?

MIGRAINE 250-250-65 MG CPLT (NDC 24385036571) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.